PDF(Pubmed)
Abstract：
Histological evidence of pancreatitis is commonly found in necropsy studies in cats. A clinical diagnosis of pancreatitis is challenging due to nonspecific clinical signs, a lack of diagnostic lipase cutoffs, and frequent presence of multiple diseases. It is still unknown how often pancreatitis alone is found in sick cats and how often clinicopathological evidence of pancreatitis in sick cats does not lead to a clinical diagnosis of pancreatitis. Our aims were to evaluate the extent of comorbidities in cats with suspected pancreatitis, evaluate how often sick cats with hyperlipasemia are diagnosed only with non-pancreatic diseases, and compare their clinical findings. Medical records of 563 client-owned hospitalized cats with available lipase activity measurement (LIPC Roche) > 30 U/L (RI, 6-26) were searched and medical diagnoses recorded and grouped by organ system. Clinicopathological findings were compared between cats with pancreatitis alone (PA), pancreatitis with concurrent disease (PD), and no suspected pancreatitis (NP). We found that PA was present in 33 (6%) cats, 159 cats (28%) were in the PD group, and 371 cats (66%) had no suspected pancreatitis (NP). Clinical, laboratory, and ultrasonographic findings did not differ between PA and PD cats. Lipase activities did not differ between the three groups. The most common disease categories in PD and NP cats were gastrointestinal, hepatobiliary, renal/urinary, and endocrine, and renal/urinary, gastrointestinal, cardiac, and musculoskeletal, respectively. We conclude that cats are rarely hospitalized because of suspected pancreatitis alone, and PA cats did not differ clinically from PD cats. Hyperlipasemia in sick cats without a diagnosis of pancreatitis may be due to a reactive pancreatopathy or preexisting chronic pancreatitis.
摘要：
胰腺炎的组织学证据通常在猫的尸检研究中发现。由于非特异性临床体征，胰腺炎的临床诊断具有挑战性。缺乏诊断脂肪酶切断，和常见的多种疾病。尚不清楚在病猫中发现单独的胰腺炎的频率，以及在病猫中发现胰腺炎的临床病理证据的频率不能导致胰腺炎的临床诊断。我们的目的是评估疑似胰腺炎的猫的合并症程度，评估患有高脂血症的患病猫仅被诊断为非胰腺疾病的频率，并比较他们的临床发现。563只客户拥有的住院猫的医疗记录，可用的脂肪酶活性测量（LIPCRoche）>30U/L（RI，6-26）进行搜索，并按器官系统记录和分组医疗诊断。临床病理结果在单独患有胰腺炎（PA）的猫之间进行了比较，胰腺炎并发疾病（PD），无可疑胰腺炎（NP）。我们发现PA存在于33只（6%）猫中，PD组中有159只猫（28％），371只猫（66％）没有可疑的胰腺炎（NP）。临床,实验室,PA和PD猫的超声检查结果没有差异。三组之间的脂肪酶活性没有差异。PD和NP猫中最常见的疾病类别是胃肠道疾病，肝胆,肾/尿,和内分泌，和肾/尿，胃肠,心脏,和骨骼肌肉，分别。我们得出的结论是，猫很少因为怀疑胰腺炎而住院，PA猫在临床上与PD猫没有差异。未诊断为胰腺炎的病猫高脂血症可能是由于反应性胰腺炎或先前存在的慢性胰腺炎。
