Abstract：
Perfluoroalkyl acids (PFAAs) are emerging pollutants that endangers food safety. Developing methods for the selective determination of trace PFAAs in complex samples remains challenging. Herein, an ionic liquid modified porous imprinted phenolic resin-dispersive filter extraction-liquid chromatography-tandem mass spectrometry (IL-PIPR-DFE-LC-MS/MS) method was developed for the determination of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) in eggs. The new IL-PIPR adsorbent was prepared at room temperature, which avoids the disorder and instability of the template at high temperatures. The imprinting factor of IL-PIPR for PFOA and PFOS exceeded 7.3. DFE, combined with IL-PIPR (15 mg), was used to extract PFOA and PFOS from eggs within 15 min. The established method exhibits low limits of detection (0.01-0.02 ng/g) and high recoveries (84.7%-104.7%), which surpass those of previously reported methods. This work offers a new approach to explore advanced imprinted adsorbents for PFAAs, efficient sample pretreatment technique, and analytical method for pollutants in foods.
摘要：
全氟烷基酸（PFAA）是危害食品安全的新兴污染物。开发用于选择性测定复杂样品中痕量PFAA的方法仍然具有挑战性。在这里，建立了离子液体改性多孔印迹酚醛树脂-分散过滤萃取-液相色谱-串联质谱(IL-PIPR-DFE-LC-MS/MS)测定鸡蛋中全氟辛酸(PFOA)和全氟辛烷磺酸(PFOS)的方法。在室温下制备了新型IL-PIPR吸附剂,这避免了模板在高温下的无序和不稳定。PFOA和PFOS的IL-PIPR印迹因子超过7.3。DFE,联合IL-PIPR（15mg），用于在15分钟内从卵中提取PFOA和PFOS。方法检出限低(0.01-0.02ng/g),回收率高(84.7%-104.7%),超过了以前报道的方法。这项工作为探索用于PFAA的先进印迹吸附剂提供了一种新的方法，高效的样品预处理技术，食品中污染物的分析方法。
