UNASSIGNED: Participants completed a horizontal saccade task and their gaze was measured using a pupil-based eye tracker. Oscillations occurring in the 80 to 200 ms post-saccadic period were described with a damped oscillation model. We compared the amplitude, decay time constant, and frequency of the PSOs for the three different groups. We also examined the correlation between these PSO parameters and the amplitude, peak velocity, and final deceleration of the preceding saccades.
UNASSIGNED: Subjects with vision loss (AMD, n = 6, and RP, n = 5) had larger oscillation amplitudes, longer decay constants, and lower frequencies than subjects with NV (n = 7). The oscillation amplitudes increased with increases in saccade deceleration in all three groups. The other PSO parameters, however, did not show consistent correlations with either saccade amplitude or peak velocity.
UNASSIGNED: Post-saccadic fixation stability in AMD and RP is reduced due to abnormal PSOs. The differences with respect to NV are not due to differences in saccade kinematics, suggesting that anatomic and neuronal variations affect the suspension of the iris and the lens in the patients\' eyes.
■参与者完成了水平扫视任务,并使用基于瞳孔的眼睛跟踪器测量了他们的凝视。用阻尼振荡模型描述了扫视后80至200ms周期内发生的振荡。我们比较了振幅,衰减时间常数,和三个不同组的PSO频率。我们还检查了这些PSO参数与振幅之间的相关性,峰值速度,和前面扫视的最后减速。
■视力丧失的受试者(AMD,n=6,RP,n=5)具有较大的振荡幅度,更长的衰减常数,频率低于NV受试者(n=7)。在所有三组中,振荡幅度都随着扫视减速的增加而增加。其他PSO参数,然而,与扫视幅度或峰值速度均未显示一致的相关性。
■由于异常的PSO,AMD和RP的扫视后固定稳定性降低。关于NV的差异不是由于扫视运动学的差异,这表明解剖和神经元变异会影响患者眼虹膜和晶状体的悬吊。