Abstract：
OBJECTIVE: Antimicrobial resistance is an alarming global public health concern, threatening the effective treatment of common infections. This phenomenon is driven by the improper prescription of antibiotics. This study aimed to elucidate the patterns of antibiotic prescription in implant dentistry among European dentists and their awareness of antibiotic resistance.
METHODS: An anonymous online validated questionnaire was distributed via e-mail to 6431 recipients through the European Association for Osseointegration. It comprised of 17 structured questions investigating demographic variables, working environment, clinical experience, attitude towards antibiotic prescription in particular in relation to implant dentistry and COVID-19 pandemic, and awareness of antibiotic resistance. Data were collected from April to May 2023.
RESULTS: 281 dentists from 33 European countries completed the survey. Almost 80% affirmed to routinely prescribe antibiotics as prophylaxis as well as after dental implant placement, especially in medically compromised patients or in cases of bone grafting. Amoxicillin, alone (61%) or in combination with clavulanic acid (56%), was the most common antibiotic of choice. Awareness of penicillin resistance among respondents was high. For peri-implantitis treatment, more than half reported the use of systemic antibiotics. The large majority (95%) did not prescribe more antibiotics since the beginning of COVID-19 pandemic. Less than 40% declared to follow national guidelines for antibiotic prescription.
CONCLUSIONS: This survey revealed a high prescription rate of antibiotics in implant dentistry, despite the awareness about antibiotic resistance among the respondents. The development and adherence to European guidelines has been identified as a potential strategy for improving antimicrobial stewardship.
METHODS: An anonymous online validated questionnaire was distributed via e-mail to 6431 recipients through the European Association for Osseointegration. It comprised of 17 structured questions investigating demographic variables, working environment, clinical experience, attitude towards antibiotic prescription in particular in relation to implant dentistry and COVID-19 pandemic, and awareness of antibiotic resistance. Data were collected from April to May 2023.
RESULTS: 281 dentists from 33 European countries completed the survey. Almost 80% affirmed to routinely prescribe antibiotics as prophylaxis as well as after dental implant placement, especially in medically compromised patients or in cases of bone grafting. Amoxicillin, alone (61%) or in combination with clavulanic acid (56%), was the most common antibiotic of choice. Awareness of penicillin resistance among respondents was high. For peri-implantitis treatment, more than half reported the use of systemic antibiotics. The large majority (95%) did not prescribe more antibiotics since the beginning of COVID-19 pandemic. Less than 40% declared to follow national guidelines for antibiotic prescription.
CONCLUSIONS: This survey revealed a high prescription rate of antibiotics in implant dentistry, despite the awareness about antibiotic resistance among the respondents. The development and adherence to European guidelines has been identified as a potential strategy for improving antimicrobial stewardship.
摘要：
目的：抗菌素耐药性是一个令人担忧的全球公共卫生问题，威胁到常见感染的有效治疗。这种现象是由抗生素处方不当引起的。这项研究旨在阐明欧洲牙医中植入牙科中抗生素处方的模式及其对抗生素耐药性的认识。
方法：通过欧洲骨整合协会通过电子邮件向6431名收件人分发了一份匿名在线验证问卷。它由17个结构化的问题组成，调查人口统计变量，工作环境,临床经验,对抗生素处方的态度，特别是与植入牙科和COVID-19大流行有关的态度，以及对抗生素耐药性的认识。数据收集时间为2023年4月至5月。
结果：来自33个欧洲国家的281名牙医完成了调查。几乎80％的人确认常规开抗生素作为预防措施以及在种植牙之后，尤其是在医学上受损的患者或植骨的情况下。阿莫西林,单独（61％）或与克拉维酸（56％）联合使用，是最常见的抗生素选择。受访者对青霉素耐药性的认识很高。对于种植体周围炎治疗，超过一半的人报告使用了全身性抗生素.自COVID-19大流行以来，绝大多数(95%)没有开出更多的抗生素。不到40％的人宣布遵循国家抗生素处方指南。
结论：这项调查显示，种植牙科中抗生素的处方率高，尽管受访者对抗生素耐药性的认识。制定和遵守欧洲指南已被确定为改善抗菌药物管理的潜在策略。
方法：通过欧洲骨整合协会通过电子邮件向6431名收件人分发了一份匿名在线验证问卷。它由17个结构化的问题组成，调查人口统计变量，工作环境,临床经验,对抗生素处方的态度，特别是与植入牙科和COVID-19大流行有关的态度，以及对抗生素耐药性的认识。数据收集时间为2023年4月至5月。
结果：来自33个欧洲国家的281名牙医完成了调查。几乎80％的人确认常规开抗生素作为预防措施以及在种植牙之后，尤其是在医学上受损的患者或植骨的情况下。阿莫西林,单独（61％）或与克拉维酸（56％）联合使用，是最常见的抗生素选择。受访者对青霉素耐药性的认识很高。对于种植体周围炎治疗，超过一半的人报告使用了全身性抗生素.自COVID-19大流行以来，绝大多数(95%)没有开出更多的抗生素。不到40％的人宣布遵循国家抗生素处方指南。
结论：这项调查显示，种植牙科中抗生素的处方率高，尽管受访者对抗生素耐药性的认识。制定和遵守欧洲指南已被确定为改善抗菌药物管理的潜在策略。
