PDF(Pubmed)
Abstract：
The two patients included in the study had mixed and refractory post-tuberculosis tracheobronchial stenosis (PTTS), having experienced unsuccessful interventional therapies such as balloon dilation and V-shaped stent placement before the operation. Following the secure placement of L-shaped silicone stents, examinations with a fiberbronchoscope during the first and third months post-operation revealed a significant reduction in bronchial mucosa inflammation for both patients. Additionally, the opening diameter of the upper and lower branch segments increased, and chest CT scans indicated a noticeable absorption of left pulmonary lesions. Three months post-operation, fiberbronchoscopy confirmed the stable fixation of the stent without any movement. The patients exhibited substantial improvements in pulmonary function, dyspnea index, and blood gas analysis, with no reported adverse complications. After 7 months, a follow-up fiberbronchoscope for one case revealed excellent stent fixation. Simultaneously, the chest CT scan indicated favorable re-expansion. The placement of L-shaped silicone stents proves effective in preventing displacement, alleviating airway stenosis or obstruction, and ensuring the safety and efficacy of PTTS treatment - particularly in cases where V-shaped silicone stent placement has failed. To our knowledge, this is the first study describing the L-shaped silicone stent in two patients with PTTS.
Successful treatment of severe airway narrowing due to tuberculosis using special L-shaped silicone stentsThis article tells the story of two patients who suffered from a complex lung condition called post-tuberculosis tracheobronchial stenosis (PTTS). Imagine your airways - the tubes that carry air to your lungs - getting severely scarred and narrowed due to a past bout with tuberculosis. These two patients had tried previous treatments like balloon dilation (where a small balloon is inflated inside the narrowed airway to widen it) and using V-shaped stents (flexible supports placed in the airway to keep it open), but these methods didn’t provide lasting relief. In this innovative approach, doctors used L-shaped silicone stents specifically designed to fit in the affected parts of the patients’ airways. After placing these stents, regular checks showed remarkable improvements. The swelling in the airway lining reduced significantly, and the openings leading to the upper and lower parts of the lungs got wider. Chest X-rays (CT scans) even showed that the patient’s left lung was healing well. Three months later, the stents stayed firmly in place, and neither patient experienced any problems. Breathing became easier, lung function tests improved, and blood tests showed better oxygen levels. Seven months down the line, one patient continued to do extremely well, with the stent securely fixed and the chest scan showing good lung expansion. This groundbreaking study shows that using L-shaped silicone stents can effectively treat PTTS when other methods fail. Not only do they stay in place, preventing blockages, but they also safely and effectively alleviate narrowing of the airways. It’s the first time such L-shaped stents have been used successfully in PTTS patients, offering new hope for those facing similar challenges.
Successful treatment of severe airway narrowing due to tuberculosis using special L-shaped silicone stentsThis article tells the story of two patients who suffered from a complex lung condition called post-tuberculosis tracheobronchial stenosis (PTTS). Imagine your airways - the tubes that carry air to your lungs - getting severely scarred and narrowed due to a past bout with tuberculosis. These two patients had tried previous treatments like balloon dilation (where a small balloon is inflated inside the narrowed airway to widen it) and using V-shaped stents (flexible supports placed in the airway to keep it open), but these methods didn’t provide lasting relief. In this innovative approach, doctors used L-shaped silicone stents specifically designed to fit in the affected parts of the patients’ airways. After placing these stents, regular checks showed remarkable improvements. The swelling in the airway lining reduced significantly, and the openings leading to the upper and lower parts of the lungs got wider. Chest X-rays (CT scans) even showed that the patient’s left lung was healing well. Three months later, the stents stayed firmly in place, and neither patient experienced any problems. Breathing became easier, lung function tests improved, and blood tests showed better oxygen levels. Seven months down the line, one patient continued to do extremely well, with the stent securely fixed and the chest scan showing good lung expansion. This groundbreaking study shows that using L-shaped silicone stents can effectively treat PTTS when other methods fail. Not only do they stay in place, preventing blockages, but they also safely and effectively alleviate narrowing of the airways. It’s the first time such L-shaped stents have been used successfully in PTTS patients, offering new hope for those facing similar challenges.
摘要：
纳入研究的2例患者患有混合型和难治性结核后气管支气管狭窄（PTTS），术前经历过球囊扩张和V形支架置入等不成功的介入治疗。安全放置L形硅胶支架后,术后第1个月和第3个月的纤维支气管镜检查显示，两名患者的支气管粘膜炎症均显着减少。此外,上部和下部分支段的开口直径增加，胸部CT扫描显示左肺病变明显吸收。手术后三个月，纤维支气管镜检查证实支架固定稳定，无任何运动。患者的肺功能有了实质性的改善，呼吸困难指数,和血气分析,没有报告的不良并发症。7个月后,1例纤维支气管镜随访显示支架固定效果良好。同时,胸部CT扫描显示有利的再扩张。L形硅胶支架的放置证明可有效防止移位，缓解气道狭窄或阻塞，并确保PTTS治疗的安全性和有效性-特别是在V形硅胶支架置入失败的情况下。据我们所知,这是第一项描述2例PTTS患者使用L型硅胶支架的研究.
使用特殊的L形硅胶支架成功治疗因肺结核引起的严重气道狭窄本文讲述了两名患有肺结核后气管支气管狭窄（PTS）的复杂肺部疾病的患者的故事。想象一下你的气道-将空气输送到肺部的管道-由于过去的肺结核发作而严重伤痕累累并变窄。这两名患者尝试了以前的治疗方法，如球囊扩张（在狭窄的气道内膨胀一个小球囊以使其变宽）和使用V形支架（放置在气道中以保持其打开的柔性支撑），但是这些方法并不能提供持久的缓解。在这种创新的方法中，医生使用了专门设计用于患者气道受影响部位的L形硅胶支架。放置这些支架后，定期检查显示出显着的改善。气道内膜肿胀明显减轻，通向肺部上部和下部的开口变得更宽。胸部X光片（CT扫描）甚至显示患者的左肺愈合良好。三个月后,支架牢牢地保持在原位，两个病人都没有遇到任何问题。呼吸变得更容易，肺功能检查有所改善，血液测试显示氧气水平更好。七个月后，一名患者继续做得非常好，支架牢固固定，胸部扫描显示肺部扩张良好。这项开创性的研究表明，当其他方法失败时，使用L形硅胶支架可以有效治疗PTTS。他们不仅呆在原地，防止堵塞，但它们也安全有效地缓解了气道狭窄。这是第一次在PTTS患者中成功使用这种L形支架，为面临类似挑战的人们带来新的希望。
使用特殊的L形硅胶支架成功治疗因肺结核引起的严重气道狭窄本文讲述了两名患有肺结核后气管支气管狭窄（PTS）的复杂肺部疾病的患者的故事。想象一下你的气道-将空气输送到肺部的管道-由于过去的肺结核发作而严重伤痕累累并变窄。这两名患者尝试了以前的治疗方法，如球囊扩张（在狭窄的气道内膨胀一个小球囊以使其变宽）和使用V形支架（放置在气道中以保持其打开的柔性支撑），但是这些方法并不能提供持久的缓解。在这种创新的方法中，医生使用了专门设计用于患者气道受影响部位的L形硅胶支架。放置这些支架后，定期检查显示出显着的改善。气道内膜肿胀明显减轻，通向肺部上部和下部的开口变得更宽。胸部X光片（CT扫描）甚至显示患者的左肺愈合良好。三个月后,支架牢牢地保持在原位，两个病人都没有遇到任何问题。呼吸变得更容易，肺功能检查有所改善，血液测试显示氧气水平更好。七个月后，一名患者继续做得非常好，支架牢固固定，胸部扫描显示肺部扩张良好。这项开创性的研究表明，当其他方法失败时，使用L形硅胶支架可以有效治疗PTTS。他们不仅呆在原地，防止堵塞，但它们也安全有效地缓解了气道狭窄。这是第一次在PTTS患者中成功使用这种L形支架，为面临类似挑战的人们带来新的希望。
