Abstract：
OBJECTIVE: There are several case reports describing patients with both optic nerve hypoplasia/septo-optic-pituitary dysplasia (ONH/SOD) and gastroschisis (GS). Our aim was to investigate whether ONH/SOD is associated with GS.
METHODS: A retrospective population-based study was undertaken using the Population Research Data Repository at the Manitoba Center for Health Policy in Manitoba, Canada to investigate if any patient with ONH/SOD also had GS. In addition, Winnipeg\'s Surgical Database of Outcomes and Management (WiSDOM), a hospital-based paediatric surgical database, was searched to ascertain if any of the patients with GS also have ONH/SOD.
RESULTS: Cases were 124 patients with ONH/SOD diagnosed during 1990-2019. None had GS. The surgical database had 188 patients from Manitoba with GS during 1991-2019. None had ONH/SOD.
CONCLUSIONS: There does not appear to be an association between ONH/SOD and GS in our cohorts of patients with these two disorders.
METHODS: A retrospective population-based study was undertaken using the Population Research Data Repository at the Manitoba Center for Health Policy in Manitoba, Canada to investigate if any patient with ONH/SOD also had GS. In addition, Winnipeg\'s Surgical Database of Outcomes and Management (WiSDOM), a hospital-based paediatric surgical database, was searched to ascertain if any of the patients with GS also have ONH/SOD.
RESULTS: Cases were 124 patients with ONH/SOD diagnosed during 1990-2019. None had GS. The surgical database had 188 patients from Manitoba with GS during 1991-2019. None had ONH/SOD.
CONCLUSIONS: There does not appear to be an association between ONH/SOD and GS in our cohorts of patients with these two disorders.
摘要：
目的：有几个病例报告描述了视神经发育不全/视垂体发育不良（ONH/SOD）和胃裂（GS）的患者。我们的目的是调查ONH/SOD是否与GS相关。
方法：使用曼尼托巴省卫生政策中心的人口研究数据存储库进行了一项基于人群的回顾性研究。加拿大调查是否有ONH/SOD患者也有GS。此外,温尼伯的结果和管理外科数据库(WiSDOM)，基于医院的儿科外科数据库，进行搜索，以确定是否有任何GS患者也有ONH/SOD。
结果：病例为1990-2019年诊断为ONH/SOD的124例患者。没有GS。手术数据库在1991-2019年期间有188名来自曼尼托巴省的GS患者。无ONH/SOD。
结论：在我们的ONH/SOD和GS这两种疾病的患者队列中，似乎没有相关性。
方法：使用曼尼托巴省卫生政策中心的人口研究数据存储库进行了一项基于人群的回顾性研究。加拿大调查是否有ONH/SOD患者也有GS。此外,温尼伯的结果和管理外科数据库(WiSDOM)，基于医院的儿科外科数据库，进行搜索，以确定是否有任何GS患者也有ONH/SOD。
结果：病例为1990-2019年诊断为ONH/SOD的124例患者。没有GS。手术数据库在1991-2019年期间有188名来自曼尼托巴省的GS患者。无ONH/SOD。
结论：在我们的ONH/SOD和GS这两种疾病的患者队列中，似乎没有相关性。
