{Reference Type}: Journal Article
{Title}: Gastroschisis and septo-optic-pituitary dysplasia: Is there an association?
{Author}: Salman MS;Ruth CA;Yogendran MS;Zrinyi A;Morris M;
{Journal}: J Paediatr Child Health
{Volume}: 0
{Issue}: 0
{Year}: 2024 May 23
{Factor}: 1.929
{DOI}: 10.1111/jpc.16568
{Abstract}: <B>OBJECTIVE: </B>There are several case reports describing patients with both optic nerve hypoplasia/septo-optic-pituitary dysplasia (ONH/SOD) and gastroschisis (GS). Our aim was to investigate whether ONH/SOD is associated with GS.<BR><B>METHODS: </B>A retrospective population-based study was undertaken using the Population Research Data Repository at the Manitoba Center for Health Policy in Manitoba, Canada to investigate if any patient with ONH/SOD also had GS. In addition, Winnipeg's Surgical Database of Outcomes and Management (WiSDOM), a hospital-based paediatric surgical database, was searched to ascertain if any of the patients with GS also have ONH/SOD.<BR><B>RESULTS: </B>Cases were 124 patients with ONH/SOD diagnosed during 1990-2019. None had GS. The surgical database had 188 patients from Manitoba with GS during 1991-2019. None had ONH/SOD.<BR><B>CONCLUSIONS: </B>There does not appear to be an association between ONH/SOD and GS in our cohorts of patients with these two disorders.