%0 Journal Article
%T Gastroschisis and septo-optic-pituitary dysplasia: Is there an association?
%A Salman MS
%A Ruth CA
%A Yogendran MS
%A Zrinyi A
%A Morris M
%J J Paediatr Child Health
%V 0
%N 0
%D 2024 May 23
%M 38780070
%F 1.929
%R 10.1111/jpc.16568
%X <B>OBJECTIVE: </B>There are several case reports describing patients with both optic nerve hypoplasia/septo-optic-pituitary dysplasia (ONH/SOD) and gastroschisis (GS). Our aim was to investigate whether ONH/SOD is associated with GS.<BR><B>METHODS: </B>A retrospective population-based study was undertaken using the Population Research Data Repository at the Manitoba Center for Health Policy in Manitoba, Canada to investigate if any patient with ONH/SOD also had GS. In addition, Winnipeg's Surgical Database of Outcomes and Management (WiSDOM), a hospital-based paediatric surgical database, was searched to ascertain if any of the patients with GS also have ONH/SOD.<BR><B>RESULTS: </B>Cases were 124 patients with ONH/SOD diagnosed during 1990-2019. None had GS. The surgical database had 188 patients from Manitoba with GS during 1991-2019. None had ONH/SOD.<BR><B>CONCLUSIONS: </B>There does not appear to be an association between ONH/SOD and GS in our cohorts of patients with these two disorders.