PDF(Pubmed)
Abstract：
Gastroesophageal reflux disease (GERD) is a common disease affecting millions of people worldwide. Proton pump inhibitors (PPI) are the most common drugs used to treat this acid-related disorder due to their high efficacy and fewer side effects. However, long-term use of these drugs can cause histopathological changes, including cystic dilation of gastric fundic glands. The present report describes a 53-year-old man with chronic GERD and daily use of PPIs 20 mg once a day for over 15 years. This case demonstrates the association between PPI and the development of fundic gland polyps.
摘要：
胃食管反流病(GERD)是影响全世界数百万人的常见疾病。质子泵抑制剂（PPI）是用于治疗这种酸相关疾病的最常见药物，因为它们具有高疗效和较少的副作用。然而,长期使用这些药物会引起组织病理学变化，包括胃底腺囊性扩张。本报告描述了一名53岁的患有慢性GERD的男子，每天一次使用20毫克PPI超过15年。此病例证明了PPI与胃底腺息肉的发展之间的关联。
