{Reference Type}: Case Reports
{Title}: Development of Gastric Polyps: 15 Years of Proton Pump Inhibitor Therapy.
{Author}: Cabrera Charleston M;Oscura Paredes DG;Alfaro Mendez G;Cabrera Tello JM;
{Journal}: Cureus
{Volume}: 16
{Issue}: 5
{Year}: 2024 May
暂无{DOI}: 10.7759/cureus.60814
{Abstract}: Gastroesophageal reflux disease (GERD) is a common disease affecting millions of people worldwide. Proton pump inhibitors (PPI) are the most common drugs used to treat this acid-related disorder due to their high efficacy and fewer side effects. However, long-term use of these drugs can cause histopathological changes, including cystic dilation of gastric fundic glands. The present report describes a 53-year-old man with chronic GERD and daily use of PPIs 20 mg once a day for over 15 years. This case demonstrates the association between PPI and the development of fundic gland polyps.