%0 Case Reports
%T Development of Gastric Polyps: 15 Years of Proton Pump Inhibitor Therapy.
%A Cabrera Charleston M
%A Oscura Paredes DG
%A Alfaro Mendez G
%A Cabrera Tello JM
%J Cureus
%V 16
%N 5
%D 2024 May
%M 38779437
暂无%R 10.7759/cureus.60814
%X Gastroesophageal reflux disease (GERD) is a common disease affecting millions of people worldwide. Proton pump inhibitors (PPI) are the most common drugs used to treat this acid-related disorder due to their high efficacy and fewer side effects. However, long-term use of these drugs can cause histopathological changes, including cystic dilation of gastric fundic glands. The present report describes a 53-year-old man with chronic GERD and daily use of PPIs 20 mg once a day for over 15 years. This case demonstrates the association between PPI and the development of fundic gland polyps.