PDF(Pubmed)
Abstract：
UNASSIGNED: COVID-19 is primarily known as a respiratory illness; however, many patients present to hospital without respiratory symptoms. The association between non-respiratory presentations of COVID-19 and outcomes remains unclear. We investigated risk factors and clinical outcomes in patients with no respiratory symptoms (NRS) and respiratory symptoms (RS) at hospital admission.
UNASSIGNED: This study describes clinical features, physiological parameters, and outcomes of hospitalised COVID-19 patients, stratified by the presence or absence of respiratory symptoms at hospital admission. RS patients had one or more of: cough, shortness of breath, sore throat, runny nose or wheezing; while NRS patients did not.
UNASSIGNED: Of 178,640 patients in the study, 86.4 % presented with RS, while 13.6 % had NRS. NRS patients were older (median age: NRS: 74 vs RS: 65) and less likely to be admitted to the ICU (NRS: 36.7 % vs RS: 37.5 %). NRS patients had a higher crude in-hospital case-fatality ratio (NRS 41.1 % vs. RS 32.0 %), but a lower risk of death after adjusting for confounders (HR 0.88 [0.83-0.93]).
UNASSIGNED: Approximately one in seven COVID-19 patients presented at hospital admission without respiratory symptoms. These patients were older, had lower ICU admission rates, and had a lower risk of in-hospital mortality after adjusting for confounders.
UNASSIGNED: This study describes clinical features, physiological parameters, and outcomes of hospitalised COVID-19 patients, stratified by the presence or absence of respiratory symptoms at hospital admission. RS patients had one or more of: cough, shortness of breath, sore throat, runny nose or wheezing; while NRS patients did not.
UNASSIGNED: Of 178,640 patients in the study, 86.4 % presented with RS, while 13.6 % had NRS. NRS patients were older (median age: NRS: 74 vs RS: 65) and less likely to be admitted to the ICU (NRS: 36.7 % vs RS: 37.5 %). NRS patients had a higher crude in-hospital case-fatality ratio (NRS 41.1 % vs. RS 32.0 %), but a lower risk of death after adjusting for confounders (HR 0.88 [0.83-0.93]).
UNASSIGNED: Approximately one in seven COVID-19 patients presented at hospital admission without respiratory symptoms. These patients were older, had lower ICU admission rates, and had a lower risk of in-hospital mortality after adjusting for confounders.
摘要：
■COVID-19主要被称为呼吸系统疾病；然而，许多患者到医院就诊时没有呼吸道症状。COVID-19的非呼吸道表现与结果之间的关系尚不清楚。我们调查了入院时无呼吸道症状（NRS）和呼吸道症状（RS）的患者的危险因素和临床结局。
■这项研究描述了临床特征，生理参数,住院COVID-19患者的结果，根据入院时是否有呼吸道症状进行分层。RS患者有一种或多种：咳嗽，呼吸急促,喉咙痛,流鼻涕或喘息；而NRS患者没有。
■在这项研究中的178,640名患者中，86.4%出现在RS中，13.6%有NRS。NRS患者年龄较大（中位年龄：NRS：74vsRS：65），不太可能进入ICU（NRS：36.7％vsRS：37.5％）。NRS患者的住院病死率较高（NRS41.1％与RS32.0%)，但在校正混杂因素后死亡风险较低(HR0.88[0.83-0.93])。
■大约七分之一的COVID-19患者入院时出现呼吸道症状。这些病人年龄较大,ICU入院率较低，并且在校正混杂因素后,院内死亡率的风险较低.
■这项研究描述了临床特征，生理参数,住院COVID-19患者的结果，根据入院时是否有呼吸道症状进行分层。RS患者有一种或多种：咳嗽，呼吸急促,喉咙痛,流鼻涕或喘息；而NRS患者没有。
■在这项研究中的178,640名患者中，86.4%出现在RS中，13.6%有NRS。NRS患者年龄较大（中位年龄：NRS：74vsRS：65），不太可能进入ICU（NRS：36.7％vsRS：37.5％）。NRS患者的住院病死率较高（NRS41.1％与RS32.0%)，但在校正混杂因素后死亡风险较低(HR0.88[0.83-0.93])。
■大约七分之一的COVID-19患者入院时出现呼吸道症状。这些病人年龄较大,ICU入院率较低，并且在校正混杂因素后,院内死亡率的风险较低.
