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Abstract：
BACKGROUND: Radiation dose measurement is an essential part of radiotherapy to verify the correct delivery of doses to patients and ensure patient safety. Recent advancements in radiotherapy technology have highlighted the need for fast and precise dosimeters. Technologies like FLASH radiotherapy and magnetic-resonance linear accelerators (MR-LINAC) demand dosimeters that can meet their unique requirements. One promising solution is the plastic scintillator-based dosimeter with high spatial resolution and real-time dose output. This study explores the feasibility of using the LuSy dosimeter, an in-house developed plastic scintillator dosimeter for dose verification across various radiotherapy techniques, including conformal radiotherapy (CRT), intensity-modulated radiation therapy (IMRT), volumetric-modulated arc therapy (VMAT), and stereotactic radiosurgery (SRS).
METHODS: A new dosimetry system, comprising a new plastic scintillator as the sensing material, was developed and characterized for radiotherapy beams. Treatment plans were created for conformal radiotherapy, IMRT, VMAT, and SRS and delivered to a phantom. LuSy dosimeter was used to measure the delivered dose for each plan on the surface of the phantom and inside the target volumes. Then, LuSy measurements were compared against an ionization chamber, MOSFET dosimeter, radiochromic films, and dose calculated using the treatment planning system (TPS).
RESULTS: For CRT, surface dose measurement by LuSy dosimeter showed a deviation of -5.5% and -5.4% for breast and abdomen treatment from the TPS, respectively. When measuring inside the target volume for IMRT, VMAT, and SRS, the LuSy dosimeter produced a mean deviation of -3.0% from the TPS. Surface dose measurement resulted in higher TPS discrepancies where the deviations for IMRT, VMAT, and SRS were -2.0%, -19.5%, and 16.1%, respectively.
CONCLUSIONS: The LuSy dosimeter was feasible for measuring radiotherapy doses for various treatment techniques. Treatment delivery verification enables early error detection, allowing for safe treatment delivery for radiotherapy patients.
METHODS: A new dosimetry system, comprising a new plastic scintillator as the sensing material, was developed and characterized for radiotherapy beams. Treatment plans were created for conformal radiotherapy, IMRT, VMAT, and SRS and delivered to a phantom. LuSy dosimeter was used to measure the delivered dose for each plan on the surface of the phantom and inside the target volumes. Then, LuSy measurements were compared against an ionization chamber, MOSFET dosimeter, radiochromic films, and dose calculated using the treatment planning system (TPS).
RESULTS: For CRT, surface dose measurement by LuSy dosimeter showed a deviation of -5.5% and -5.4% for breast and abdomen treatment from the TPS, respectively. When measuring inside the target volume for IMRT, VMAT, and SRS, the LuSy dosimeter produced a mean deviation of -3.0% from the TPS. Surface dose measurement resulted in higher TPS discrepancies where the deviations for IMRT, VMAT, and SRS were -2.0%, -19.5%, and 16.1%, respectively.
CONCLUSIONS: The LuSy dosimeter was feasible for measuring radiotherapy doses for various treatment techniques. Treatment delivery verification enables early error detection, allowing for safe treatment delivery for radiotherapy patients.
摘要：
背景：辐射剂量测量是放射治疗的必不可少的部分，以验证向患者正确递送剂量并确保患者安全。放射治疗技术的最新进展突出了对快速和精确剂量计的需求。像FLASH放射治疗和磁共振线性加速器(MR-LINAC)这样的技术需要能够满足其独特要求的剂量计。一种有前途的解决方案是具有高空间分辨率和实时剂量输出的基于塑料闪烁体的剂量计。本研究探讨了使用LuSy剂量计的可行性，内部开发的塑料闪烁体剂量计，用于各种放射治疗技术的剂量验证，包括适形放射治疗（CRT），调强放射治疗（IMRT），体积调制电弧治疗（VMAT），和立体定向放射外科（SRS）。
方法：一种新的剂量测定系统，包括一种新的塑料闪烁体作为传感材料，是为放射治疗束开发和表征的。为适形放疗制定了治疗计划，IMRT,VMAT,和SRS并传递给幻影。使用LuSy剂量计测量每个计划在体模表面上和目标体积内的递送剂量。然后，将LuSy测量值与电离室进行比较，MOSFET剂量计,辐射变色胶片,和使用治疗计划系统（TPS）计算的剂量。
结果：对于CRT，通过LuSy剂量计进行的表面剂量测量显示，乳房和腹部治疗与TPS的偏差为-5.5％和-5.4％，分别。在IMRT的目标体积内测量时，VMAT,和SRS,LuSy剂量计与TPS的平均偏差为-3.0%。表面剂量测量导致更高的TPS差异，其中IMRT的偏差，VMAT,SRS为-2.0%，-19.5%,16.1%，分别。
结论：LuSy剂量计可用于测量各种治疗技术的放疗剂量。治疗交付验证可实现早期错误检测，为放疗患者提供安全的治疗。
方法：一种新的剂量测定系统，包括一种新的塑料闪烁体作为传感材料，是为放射治疗束开发和表征的。为适形放疗制定了治疗计划，IMRT,VMAT,和SRS并传递给幻影。使用LuSy剂量计测量每个计划在体模表面上和目标体积内的递送剂量。然后，将LuSy测量值与电离室进行比较，MOSFET剂量计,辐射变色胶片,和使用治疗计划系统（TPS）计算的剂量。
结果：对于CRT，通过LuSy剂量计进行的表面剂量测量显示，乳房和腹部治疗与TPS的偏差为-5.5％和-5.4％，分别。在IMRT的目标体积内测量时，VMAT,和SRS,LuSy剂量计与TPS的平均偏差为-3.0%。表面剂量测量导致更高的TPS差异，其中IMRT的偏差，VMAT,SRS为-2.0%，-19.5%,16.1%，分别。
结论：LuSy剂量计可用于测量各种治疗技术的放疗剂量。治疗交付验证可实现早期错误检测，为放疗患者提供安全的治疗。
