Abstract：
UNASSIGNED: The diagnostic criteria for Hypersensitivity pneumonitis (HP) have changed over time. Our aim is to apply a recent diagnostic algorithm to a historical series of patients diagnosed with HP to assess its distribution according to current diagnostic criteria and the diagnostic confidence achieved.
UNASSIGNED: Application to each patient the algorithm criteria. The diagnosis was HP (≥90%), provisional high (70-89%) or low confidence (51-69%) or non-HP (unlikely) (≤50%); or HP, provisional or non-HP, if they had lung biopsy.
UNASSIGNED: 129 patients [mean age 64 ± 12 years; 79 (61.2%) women] were included of which 16 (12.4%) were diagnosed on the basis of high clinical suspicion. After applying the algorithm, 106 patients (82.2%) could be evaluated and 83 (78.3%) had a diagnosis of HP or high confidence. Lung biopsy was able to establish a diagnosis of certainty in another 21 patients and a provisional diagnosis in 9 more [total, 113 (87.6%)]. The 16 patients without strict diagnostic criteria for HP had a low confidence diagnosis. A total of 56 lung biopsies (64.4%) could have been avoided according to the new guidelines.
UNASSIGNED: The application of this algorithm achieves a high diagnostic yield in HP, significantly reducing the number of lung biopsies required.
UNASSIGNED: Application to each patient the algorithm criteria. The diagnosis was HP (≥90%), provisional high (70-89%) or low confidence (51-69%) or non-HP (unlikely) (≤50%); or HP, provisional or non-HP, if they had lung biopsy.
UNASSIGNED: 129 patients [mean age 64 ± 12 years; 79 (61.2%) women] were included of which 16 (12.4%) were diagnosed on the basis of high clinical suspicion. After applying the algorithm, 106 patients (82.2%) could be evaluated and 83 (78.3%) had a diagnosis of HP or high confidence. Lung biopsy was able to establish a diagnosis of certainty in another 21 patients and a provisional diagnosis in 9 more [total, 113 (87.6%)]. The 16 patients without strict diagnostic criteria for HP had a low confidence diagnosis. A total of 56 lung biopsies (64.4%) could have been avoided according to the new guidelines.
UNASSIGNED: The application of this algorithm achieves a high diagnostic yield in HP, significantly reducing the number of lung biopsies required.
摘要：
■过敏性肺炎（HP）的诊断标准随时间而变化。我们的目标是将最近的诊断算法应用于一系列诊断为HP的历史患者，以根据当前的诊断标准和所获得的诊断置信度来评估其分布。
■对每个患者应用算法标准。诊断为HP（≥90%），临时高（70-89％）或低置信度（51-69％）或非HP（不太可能）（≤50％）；或HP，临时或非HP，如果他们做了肺活检.
■。包括129例患者[平均年龄64±12岁；79例（61.2％）妇女]，其中16例（12.4％）是根据高度临床怀疑诊断的。应用算法后，可以评估106例患者（82.2％），其中83例（78.3％）诊断为HP或高置信度。肺活检能够在另外21例患者中建立确定性诊断，在另外9例患者中建立临时诊断[总计，113（87.6%）]。没有严格的HP诊断标准的16例患者诊断可信度低。根据新指南，总共可以避免56例肺活检（64.4％）。
■该算法的应用在H，显着减少所需的肺活检数量。
■对每个患者应用算法标准。诊断为HP（≥90%），临时高（70-89％）或低置信度（51-69％）或非HP（不太可能）（≤50％）；或HP，临时或非HP，如果他们做了肺活检.
■。包括129例患者[平均年龄64±12岁；79例（61.2％）妇女]，其中16例（12.4％）是根据高度临床怀疑诊断的。应用算法后，可以评估106例患者（82.2％），其中83例（78.3％）诊断为HP或高置信度。肺活检能够在另外21例患者中建立确定性诊断，在另外9例患者中建立临时诊断[总计，113（87.6%）]。没有严格的HP诊断标准的16例患者诊断可信度低。根据新指南，总共可以避免56例肺活检（64.4％）。
■该算法的应用在H，显着减少所需的肺活检数量。
