{Reference Type}: Journal Article
{Title}: Hypersensitivity pneumonitis: application of a new diagnostic algorithm to a time series of the disease.
{Author}: Casal A;Suárez-Antelo J;Riveiro V;Ferreiro L;Rodríguez-García C;de Alegría AM;Antúnez JR;Tobes ME;Otero B;Rodríguez-Núñez N;Álvarez-Dobaño JM;Vargas-Osorio K;Gude F;Valdés L;
{Journal}: Expert Rev Respir Med
{Volume}: 18
{Issue}: 3
{Year}: 2024 Mar-Apr 30
{Factor}: 4.3
{DOI}: 10.1080/17476348.2024.2358939
{Abstract}: <B>UNASSIGNED: </B>The diagnostic criteria for Hypersensitivity pneumonitis (HP) have changed over time. Our aim is to apply a recent diagnostic algorithm to a historical series of patients diagnosed with HP to assess its distribution according to current diagnostic criteria and the diagnostic confidence achieved.<BR><B>UNASSIGNED: </B>Application to each patient the algorithm criteria. The diagnosis was HP (≥90%), provisional high (70-89%) or low confidence (51-69%) or non-HP (unlikely) (≤50%); or HP, provisional or non-HP, if they had lung biopsy.<BR><B>UNASSIGNED: </B>129 patients [mean age 64 ± 12 years; 79 (61.2%) women] were included of which 16 (12.4%) were diagnosed on the basis of high clinical suspicion. After applying the algorithm, 106 patients (82.2%) could be evaluated and 83 (78.3%) had a diagnosis of HP or high confidence. Lung biopsy was able to establish a diagnosis of certainty in another 21 patients and a provisional diagnosis in 9 more [total, 113 (87.6%)]. The 16 patients without strict diagnostic criteria for HP had a low confidence diagnosis. A total of 56 lung biopsies (64.4%) could have been avoided according to the new guidelines.<BR><B>UNASSIGNED: </B>The application of this algorithm achieves a high diagnostic yield in HP, significantly reducing the number of lung biopsies required.