Abstract：
The burden of treatment (BOT) related to propranolol treatment for infantile hemangiomas (IH) has never previously been explored. A modified validated questionnaire, the Treatment Burden Questionnaire, and one-on-one semi-structured interviews were used to assess the BOT for propranolol for IH. Out of 80 caregivers, the overall burden score was very low at 1.2 out of 10; thematic analysis of interviews grouped themes into administration, monitoring, financial, and associated anomalies. The BOT of propranolol for IH is very low but could be reduced further by offering age-based risk stratification related to feeding frequency and risk of hypoglycemia, pragmatic advice around timing of doses before sleep, and reducing frequency of vital sign monitoring.
摘要：
以前从未探索过与普萘洛尔治疗婴儿血管瘤（IH）相关的治疗负担（BOT）。修改后的验证问卷，治疗负担问卷，和一对一半结构化访谈用于评估普萘洛尔用于IH的BOT。在80名护理人员中，总体负担得分非常低，为10分之1.2；访谈的主题分析将主题分为行政管理，监测,金融,和相关的异常。普萘洛尔治疗IH的BOT非常低，但可以通过提供与喂养频率和低血糖风险相关的基于年龄的风险分层来进一步降低。关于睡前剂量时间的务实建议，减少生命体征监测的频率。
