Abstract：
BACKGROUND: Colorectal carcinoma is commonly diagnosed and accounts for an important cause of cancerrelated mortality worldwide. Despite that literature has shown the superiority of laparoscopic surgery, with improved short-term clinical benefits and equivalent oncological outcomes compared with open surgery for colorectal cancer, most cases are operated by open approach. The purpose of this study was to compare the clinical and pathological outcomes between laparoscopic and open colorectal cancer surgery at our institution.
METHODS: 126 patients who had operations for colorectal cancers were identified. Patients \' clinical data, surgery type and details, postoperative early clinical outcomes and histology reports were retrieved from the database and retrospectively reviewed. Statistical analysis was used to assess the differences between laparoscopy and open approach in terms of clinical and oncological outcomes.
RESULTS: Significant advantages were associated with minimally invasive colorectal surgery, with shorter postoperative hospital stay, less incidence of medical complications and improved survival. There were no statistically significant differences between both groups in pathological parameters, namely, number of retrieved lymph nodes and margins.
CONCLUSIONS: In the hands of skilled trained surgeons, laparoscopic surgery for colorectal cancer is oncologically safe as it showed adequate dissection and appropriate number of resected lymph nodes, and is associated with reduction in postoperative morbidity and mortality. Conversion to open surgery is a risk associated with minimally invasive surgery. However, it is reported that conversion and postoperative complications are decreasing with increased surgical experience.
CONCLUSIONS: In accordance with the current worldwide practice, our study indicates that minimally invasive surgery for colorectal cancer has the benefits of laparoscopy in terms of short-term clinical outcomes but show similar pathological outcomes in comparison to open approach. With increased surgical expertise, laparoscopic surgery is becoming the standard approach to treat colorectal cancer in our centre.
METHODS: 126 patients who had operations for colorectal cancers were identified. Patients \' clinical data, surgery type and details, postoperative early clinical outcomes and histology reports were retrieved from the database and retrospectively reviewed. Statistical analysis was used to assess the differences between laparoscopy and open approach in terms of clinical and oncological outcomes.
RESULTS: Significant advantages were associated with minimally invasive colorectal surgery, with shorter postoperative hospital stay, less incidence of medical complications and improved survival. There were no statistically significant differences between both groups in pathological parameters, namely, number of retrieved lymph nodes and margins.
CONCLUSIONS: In the hands of skilled trained surgeons, laparoscopic surgery for colorectal cancer is oncologically safe as it showed adequate dissection and appropriate number of resected lymph nodes, and is associated with reduction in postoperative morbidity and mortality. Conversion to open surgery is a risk associated with minimally invasive surgery. However, it is reported that conversion and postoperative complications are decreasing with increased surgical experience.
CONCLUSIONS: In accordance with the current worldwide practice, our study indicates that minimally invasive surgery for colorectal cancer has the benefits of laparoscopy in terms of short-term clinical outcomes but show similar pathological outcomes in comparison to open approach. With increased surgical expertise, laparoscopic surgery is becoming the standard approach to treat colorectal cancer in our centre.
摘要：
背景：结直肠癌通常被诊断为全球癌症相关死亡的重要原因。尽管文献显示了腹腔镜手术的优越性，与结直肠癌开放手术相比，改善了短期临床获益和等效的肿瘤学结果，大多数案件都是通过公开方式进行的。这项研究的目的是比较我们机构的腹腔镜和开腹结直肠癌手术的临床和病理结果。
方法：确定了126例接受结直肠癌手术的患者。患者临床数据，手术类型和细节，我们从数据库中检索术后早期临床结局和组织学报告,并进行回顾性分析.统计分析用于评估腹腔镜和开放方法在临床和肿瘤学结果方面的差异。
结果：微创结直肠手术具有显著优势，术后住院时间较短，降低并发症发生率，提高生存率。两组病理参数差异无统计学意义,即,取回的淋巴结和边缘的数量。
结论：在训练有素的外科医生手中，腹腔镜结直肠癌手术在肿瘤学上是安全的，因为它显示出足够的解剖和适当数量的切除淋巴结，并且与术后发病率和死亡率的降低有关。转换为开放手术是与微创手术相关的风险。然而,据报道，随着手术经验的增加，转换和术后并发症正在减少。
结论：根据当前的全球实践，我们的研究表明,结直肠癌微创手术在短期临床结局方面具有腹腔镜的优势,但与开腹手术相比,其病理结局相似.随着外科专业知识的增加，腹腔镜手术正在成为我们中心治疗结直肠癌的标准方法。
方法：确定了126例接受结直肠癌手术的患者。患者临床数据，手术类型和细节，我们从数据库中检索术后早期临床结局和组织学报告,并进行回顾性分析.统计分析用于评估腹腔镜和开放方法在临床和肿瘤学结果方面的差异。
结果：微创结直肠手术具有显著优势，术后住院时间较短，降低并发症发生率，提高生存率。两组病理参数差异无统计学意义,即,取回的淋巴结和边缘的数量。
结论：在训练有素的外科医生手中，腹腔镜结直肠癌手术在肿瘤学上是安全的，因为它显示出足够的解剖和适当数量的切除淋巴结，并且与术后发病率和死亡率的降低有关。转换为开放手术是与微创手术相关的风险。然而,据报道，随着手术经验的增加，转换和术后并发症正在减少。
结论：根据当前的全球实践，我们的研究表明,结直肠癌微创手术在短期临床结局方面具有腹腔镜的优势,但与开腹手术相比,其病理结局相似.随着外科专业知识的增加，腹腔镜手术正在成为我们中心治疗结直肠癌的标准方法。
