PDF(Pubmed)
Abstract：
Smokeless tobacco (SLT) poses many negative health impacts. Despite its longstanding presence in societies across the world, the health implications of SLT have only been rigorously studied in recent decades. This systematic review and meta-analysis aimed to consolidate existing research to provide a comprehensive understanding of the global prevalence of SLT use among women of reproductive age. Relevant articles were extracted from databases such as PubMed, EMBASE, Web of Science, and Scopus from their inception until November 11, 2023. Observational studies reporting the number of SLT users among women of reproductive age were included. The quality of the studies was assessed using the Joanna Briggs Institute (JBI) tool. The meta-analysis used a random-effects model to determine SLT prevalence, supported by statistical tools like forest plots, I2 statistics, and sensitivity analyses to ensure the accuracy and comprehensiveness of the results. All statistical analyses were performed in R version 4.3. From 10 studies involving 2,053,667 participants, a pooled prevalence for SLT use among women of reproductive age was found to be 9.3% (95% CI: 0.038 to 0.21), with significant heterogeneity among studies (I2 = 100%). Publication bias was suspected among the studies. Sensitivity analysis and subgroup analysis couldn\'t resolve the heterogeneity. Our analysis shows a significant prevalence of SLT use in women of reproductive age, especially in low socioeconomic and developing countries like India, Pakistan, and Nepal. For women of reproductive age, the use of smokeless tobacco (SLT) can lead to infertility, pregnancy complications, and adverse fetal outcomes, including low birth weight and preterm birth. The results highlight the necessity for specific public health measures and policy changes to decrease SLT consumption among reproductive-age women. Further studies are needed to investigate the reasons behind SLT usage in this group and to assess the impact of intervention strategies, to guide more effective public health initiatives and policies.
摘要：
无烟烟草（SLT）对健康造成许多负面影响。尽管它在世界各地的社会中长期存在，SLT对健康的影响在最近几十年才得到严格的研究.本系统综述和荟萃分析旨在巩固现有研究，以全面了解育龄妇女使用SLT的全球患病率。相关文章是从PubMed等数据库中提取的，EMBASE,WebofScience,和Scopus从成立到2023年11月11日。包括报告育龄妇女中SLT使用者数量的观察性研究。使用JoannaBriggs研究所（JBI）工具评估研究质量。荟萃分析使用随机效应模型来确定SLT患病率，在森林地块等统计工具的支持下，I2统计，和敏感性分析，以确保结果的准确性和全面性。所有统计分析均在R版本4.3中进行。从涉及2,053,667名参与者的10项研究中，育龄妇女使用SLT的合并患病率为9.3％（95％CI：0.038至0.21），研究之间具有显著的异质性(I2=100%)。研究中怀疑有发表偏倚。敏感性分析和亚组分析不能解决异质性。我们的分析表明，育龄妇女使用SLT的患病率很高，尤其是在低社会经济和像印度这样的发展中国家，巴基斯坦,和尼泊尔。对于育龄妇女来说，使用无烟烟草（SLT）会导致不孕，妊娠并发症,和不良的胎儿结局，包括低出生体重和早产。结果强调了采取特定公共卫生措施和政策变化以减少育龄妇女SLT消费的必要性。需要进一步的研究来调查该组中使用SLT的原因，并评估干预策略的影响。指导更有效的公共卫生举措和政策。
