METHODS: The study involved 141 participants, with a mean age of 18-24.5 years, 83% male (49.6% exposed to COVID-19). The ANS was measured using a composite autonomic symptom scale (COMPASS-31) questionnaire and heart rate variability (HRV) using photoplethysmography. Exposure to COVID-19 was investigated using two national health-status tracking and COVID-19 exposure applications, \"Sehhaty\" and \"Twakkalna\".
RESULTS: A significantly inverse weak correlation between COMPASS-31 scores and COVID-19 exposure (r=-0.2, p=0.04). No significant association was found between HRV and COVID-19 exposure. COMPASS-31 scores for the exposed group (median=15, n=70) were significantly higher than those for the non-exposed group (median=12, n=71), U=1,913.5, p=0.03. Height (r=-0.4, p=0.002) and gender (r=0.3, p=0.001) were moderately correlated with COMPASS-31 among the exposed group.
CONCLUSIONS: These findings indicated that exposure to COVID-19 was associated with poorer ANS scores measured via COMPASS-31. Additionally, exposure to COVID-19 resulted in higher dysautonomia symptoms than non-exposed. Height and gender differences contribute to the severity of dysautonomia among exposed people.
方法:该研究涉及141名参与者,平均年龄18-24.5岁,83%的男性(49.6%暴露于COVID-19)。使用复合自主症状量表(COMPASS-31)问卷和使用光电体积描记术测量心率变异性(HRV)。使用两个国家健康状况跟踪和COVID-19暴露应用程序对COVID-19暴露进行了调查,\"Sehhaty\"和\"Twakkalna\"。
结果:COMPASS-31评分与COVID-19暴露之间呈显著的弱负相关(r=-0.2,p=0.04)。HRV与COVID-19暴露之间没有显着关联。暴露组(中位数=15,n=70)的COMPASS-31得分明显高于非暴露组(中位数=12,n=71),U=1,913.5,p=0.03。在暴露组中,身高(r=-0.4,p=0.002)和性别(r=0.3,p=0.001)与COMPASS-31中度相关。
结论:这些结果表明,暴露于COVID-19与通过COMPASS-31测得的较差ANS评分相关。此外,与未接触的人相比,暴露于COVID-19会导致更高的自主神经障碍症状。身高和性别差异导致暴露人群自主神经障碍的严重程度。