Abstract：
BACKGROUND: To understand the experiences of adolescent and adult patients living with alopecia areata (AA) in Australia regarding symptom severity and the impact on psychosocial well-being and work/classroom productivity.
METHODS: A cross-sectional online patient survey among adolescent and adult patients diagnosed with AA was recruited via the Australia Alopecia Areata Foundation. Patient-reported outcomes were also assessed.
RESULTS: A total of 337 patients (49 adolescents; 288 adults), with a mean ± standard deviation age of 14.7 ± 1.55 and 38.9 ± 13.31 years for adolescents and adults, respectively, were included. In the group with extensive hair loss (Scalp Hair Assessment Patient-Reported Outcome, categories 3 + 4, n = 172), we observed higher emotional symptom and activity limitation scores (Alopecia Areata Patient Priority Outcomes, emotional symptoms: adults 2.5 ± 1.03, adolescents 2.2 ± 1.15; activity limitations: adults 1.4 ± 1.15, adolescents 1.2 ± 0.99). Additionally, in adults, the Alopecia Areata Symptom Impact Scale global score was 4.0 ± 2.10 (symptoms subscale score 4.1 ± 1.91; interference subscale scores 3.8 ± 2.73). Hospital Anxiety and Depression Scale scores were high across participants, irrespective of hair loss extent (adults: anxiety 9.2 ± 3.85, depression 6.6 ± 3.95; adolescents: anxiety 9.7 ± 4.65, depression 5.2 ± 3.59). Work and classroom productivity were substantially impaired due to AA, with 70.5% of adults and 57.1% of adolescents reporting activity impairment, and overall work/classroom impairment reported at 39.2% and 44.9%, respectively.
CONCLUSIONS: AA impacts the physical, emotional and psychosocial well-being of both adult and adolescent patients. More extensive hair loss more profoundly impacts those living with AA. Patients may benefit from patient-centred care approaches addressing the impact of hair loss on mental and emotional well-being, daily activities and work productivity.
METHODS: A cross-sectional online patient survey among adolescent and adult patients diagnosed with AA was recruited via the Australia Alopecia Areata Foundation. Patient-reported outcomes were also assessed.
RESULTS: A total of 337 patients (49 adolescents; 288 adults), with a mean ± standard deviation age of 14.7 ± 1.55 and 38.9 ± 13.31 years for adolescents and adults, respectively, were included. In the group with extensive hair loss (Scalp Hair Assessment Patient-Reported Outcome, categories 3 + 4, n = 172), we observed higher emotional symptom and activity limitation scores (Alopecia Areata Patient Priority Outcomes, emotional symptoms: adults 2.5 ± 1.03, adolescents 2.2 ± 1.15; activity limitations: adults 1.4 ± 1.15, adolescents 1.2 ± 0.99). Additionally, in adults, the Alopecia Areata Symptom Impact Scale global score was 4.0 ± 2.10 (symptoms subscale score 4.1 ± 1.91; interference subscale scores 3.8 ± 2.73). Hospital Anxiety and Depression Scale scores were high across participants, irrespective of hair loss extent (adults: anxiety 9.2 ± 3.85, depression 6.6 ± 3.95; adolescents: anxiety 9.7 ± 4.65, depression 5.2 ± 3.59). Work and classroom productivity were substantially impaired due to AA, with 70.5% of adults and 57.1% of adolescents reporting activity impairment, and overall work/classroom impairment reported at 39.2% and 44.9%, respectively.
CONCLUSIONS: AA impacts the physical, emotional and psychosocial well-being of both adult and adolescent patients. More extensive hair loss more profoundly impacts those living with AA. Patients may benefit from patient-centred care approaches addressing the impact of hair loss on mental and emotional well-being, daily activities and work productivity.
摘要：
背景：了解澳大利亚青少年和成年斑秃（AA）患者的症状严重程度以及对社会心理健康和工作/课堂生产力的影响。
方法：通过澳大利亚斑秃基金会对被诊断为AA的青少年和成人患者进行了一项横断面在线患者调查。还评估了患者报告的结果。
结果：总共337名患者（49名青少年；288名成年人），青少年和成人的平均±标准差年龄为14.7±1.55岁和38.9±13.31岁，分别,包括在内。在广泛脱发的组中（头皮头发评估患者报告的结果，类别3+4，n=172)，我们观察到更高的情绪症状和活动受限评分(斑秃患者优先结果，情绪症状：成人2.5±1.03，青少年2.2±1.15；活动限制：成人1.4±1.15，青少年1.2±0.99）。此外,在成年人中,斑秃症状影响量表整体评分为4.0±2.10分(症状分量表评分为4.1±1.91分;干扰分量表评分为3.8±2.73分)。医院焦虑和抑郁量表在参与者中得分很高，不论脱发程度(成人:焦虑9.2±3.85,抑郁6.6±3.95;青少年:焦虑9.7±4.65,抑郁5.2±3.59)。由于AA，工作和课堂生产力受到严重损害，70.5%的成年人和57.1%的青少年报告活动障碍，总体工作/课堂障碍报告为39.2%和44.9%，分别。
结论：AA影响身体，成人和青少年患者的情感和社会心理健康。更广泛的脱发更深刻地影响那些生活在AA。患者可能受益于以患者为中心的护理方法，解决脱发对精神和情绪健康的影响，日常活动和工作效率。
方法：通过澳大利亚斑秃基金会对被诊断为AA的青少年和成人患者进行了一项横断面在线患者调查。还评估了患者报告的结果。
结果：总共337名患者（49名青少年；288名成年人），青少年和成人的平均±标准差年龄为14.7±1.55岁和38.9±13.31岁，分别,包括在内。在广泛脱发的组中（头皮头发评估患者报告的结果，类别3+4，n=172)，我们观察到更高的情绪症状和活动受限评分(斑秃患者优先结果，情绪症状：成人2.5±1.03，青少年2.2±1.15；活动限制：成人1.4±1.15，青少年1.2±0.99）。此外,在成年人中,斑秃症状影响量表整体评分为4.0±2.10分(症状分量表评分为4.1±1.91分;干扰分量表评分为3.8±2.73分)。医院焦虑和抑郁量表在参与者中得分很高，不论脱发程度(成人:焦虑9.2±3.85,抑郁6.6±3.95;青少年:焦虑9.7±4.65,抑郁5.2±3.59)。由于AA，工作和课堂生产力受到严重损害，70.5%的成年人和57.1%的青少年报告活动障碍，总体工作/课堂障碍报告为39.2%和44.9%，分别。
结论：AA影响身体，成人和青少年患者的情感和社会心理健康。更广泛的脱发更深刻地影响那些生活在AA。患者可能受益于以患者为中心的护理方法，解决脱发对精神和情绪健康的影响，日常活动和工作效率。
