Abstract：
Actinomycetes, a diverse group of bacteria with filamentous growth characteristics, have long captivated researchers and biochemists for their prolific production of secondary metabolites. Among the myriad roles played by actinomycete secondary metabolites, their historical significance in the field of biocontrol stands out prominently. The fascinating journey begins with the discovery of antibiotics, where renowned compounds like streptomycin, tetracycline, and erythromycin revolutionized medicine and agriculture. The history of biocontrol traces its roots back to the early twentieth century, when scientists recognized the potential of naturally occurring agents to combat pests and diseases. The emergence of synthetic pesticides in the mid-twentieth century temporarily overshadowed interest in biocontrol. However, with growing environmental concerns and the realization of the negative ecological impacts of chemical pesticides, the pendulum swung back towards exploring sustainable alternatives. Beyond their historical role as antibiotics, actinomycete-produced secondary metabolites encompass a rich repertoire with biopesticide potential. The classification of these compounds based on chemical structure and mode of action is highlighted, demonstrating their versatility against both plant pathogens and insect pests. Additionally, this review provides in-depth insights into how endophytic actinomycete strains play a pivotal role in biocontrol strategies. Case studies elucidate their effectiveness in inhibiting Spodoptera spp. and nematodes through the production of bioactive compounds. By unraveling the multifunctional roles of endophytic actinomycetes, this review contributes compelling narrative knowledge to the field of sustainable agriculture, emphasizing the potential of these microbial allies in crafting effective, environmentally friendly biocontrol strategies for combating agricultural pests.
摘要：
放线菌,一组具有丝状生长特征的不同细菌，长期以来，研究人员和生物化学家因其大量生产次级代谢产物而着迷。在放线菌次生代谢产物的无数作用中，它们在生物防治领域的历史意义突出。迷人的旅程始于发现抗生素，像链霉素这样的著名化合物，四环素,红霉素彻底改变了医学和农业。生物防治的历史可以追溯到20世纪初，当科学家认识到天然存在的药剂对抗病虫害的潜力时。20世纪中叶合成农药的出现暂时掩盖了对生物防治的兴趣。然而,随着人们对环境的关注和化学农药对生态的负面影响的认识，钟摆转向探索可持续的替代方案。除了它们作为抗生素的历史作用之外，放线菌产生的次级代谢产物包含具有生物农药潜力的丰富库。重点介绍了根据化学结构和作用方式对这些化合物的分类，证明了它们对植物病原体和害虫的多功能性。此外,这篇综述提供了对内生放线菌菌株如何在生物防治策略中发挥关键作用的深入见解。案例研究阐明了它们抑制斜纹夜蛾的有效性。和线虫通过产生生物活性化合物。通过解开内生放线菌的多功能作用，这篇评论为可持续农业领域贡献了令人信服的叙事知识，强调这些微生物盟友在制造有效微生物方面的潜力，防治农业害虫的环境友好型生物防治策略。
