Abstract：
OBJECTIVE: Familial Hypercholesterolemia (FH) is an inherited disorder leading to increased risk of premature atherosclerotic cardiovascular disease. This risk can be ameliorated through adherence to pharmacological treatment and salient lifestyle behaviors (e.g., physical activity participation, healthy eating). Identifying theory-based, modifiable determinants of these behaviors may inform behavioral interventions promoting participation in FH self-management behaviors. We aimed to identify the belief-based social cognition constructs uniquely associated with intentions to perform, and actual participation in, FH self-management behaviors in the extant research.
METHODS: A systematic database search identified studies (k = 9, N = 1394) reporting relations between social cognition theory constructs and intention toward, or actual participation in, self-management behaviors in FH patients. As no studies examining prospectively-measured behaviors were identified, we tested relations among social cognition constructs, intentions, and past FH-self-management behavior using random effects multi-level meta-analysis and meta-analytic structural equation modelling.
RESULTS: We found non-zero averaged correlations among the key social cognition constructs (attitudes, norms, risk perceptions, self-efficacy), intentions, and past behavior. A meta-analytic structural equation model indicated non-zero averaged direct effects of attitudes, norms, self-efficacy, and past behavior on FH self-management behavioral intentions. There were also non-zero averaged indirect effects of past behavior on intentions mediated by the social cognition constructs.
CONCLUSIONS: Findings provide evidence to support the proposed model and highlight the importance of personal, normative, and capacity related beliefs and past experience as unique correlates of intentions to perform FH self-management behaviors. The model may signal potential constructs that could be targeted in behavioral interventions to promote participation in FH self-management behaviors.
METHODS: A systematic database search identified studies (k = 9, N = 1394) reporting relations between social cognition theory constructs and intention toward, or actual participation in, self-management behaviors in FH patients. As no studies examining prospectively-measured behaviors were identified, we tested relations among social cognition constructs, intentions, and past FH-self-management behavior using random effects multi-level meta-analysis and meta-analytic structural equation modelling.
RESULTS: We found non-zero averaged correlations among the key social cognition constructs (attitudes, norms, risk perceptions, self-efficacy), intentions, and past behavior. A meta-analytic structural equation model indicated non-zero averaged direct effects of attitudes, norms, self-efficacy, and past behavior on FH self-management behavioral intentions. There were also non-zero averaged indirect effects of past behavior on intentions mediated by the social cognition constructs.
CONCLUSIONS: Findings provide evidence to support the proposed model and highlight the importance of personal, normative, and capacity related beliefs and past experience as unique correlates of intentions to perform FH self-management behaviors. The model may signal potential constructs that could be targeted in behavioral interventions to promote participation in FH self-management behaviors.
摘要：
目的：家族性高胆固醇血症（FH）是一种遗传性疾病，可导致过早发生动脉粥样硬化性心血管疾病的风险增加。这种风险可以通过坚持药物治疗和显著的生活方式行为来改善(例如，身体活动的参与，健康饮食）。识别基于理论的，这些行为的可修改的决定因素可能会为促进参与FH自我管理行为的行为干预提供信息。我们旨在确定与执行意图唯一相关的基于信念的社会认知结构，和实际参与，现有研究中的FH自我管理行为。
方法：系统的数据库搜索确定的研究（k=9，N=1394）报告了社会认知理论建构与意图之间的关系，或实际参与，FH患者的自我管理行为。由于没有确定检查前瞻性测量行为的研究，我们测试了社会认知结构之间的关系，意图,和过去的FH自我管理行为使用随机效应多层次荟萃分析和荟萃分析结构方程模型。
结果：我们发现关键社会认知结构(态度，规范,风险认知，自我效能)，意图,过去的行为。元分析结构方程模型表明态度的平均直接效应为非零，规范,自我效能感,和过去的行为对FH自我管理行为意图的影响。过去的行为对社会认知结构介导的意图也存在非零平均间接影响。
结论：研究结果为支持所提出的模型提供了证据，并强调了个人，规范性，与能力相关的信念和过去的经验作为执行FH自我管理行为的意图的独特相关性。该模型可能预示着可能成为行为干预目标的潜在结构，以促进参与FH自我管理行为。
方法：系统的数据库搜索确定的研究（k=9，N=1394）报告了社会认知理论建构与意图之间的关系，或实际参与，FH患者的自我管理行为。由于没有确定检查前瞻性测量行为的研究，我们测试了社会认知结构之间的关系，意图,和过去的FH自我管理行为使用随机效应多层次荟萃分析和荟萃分析结构方程模型。
结果：我们发现关键社会认知结构(态度，规范,风险认知，自我效能)，意图,过去的行为。元分析结构方程模型表明态度的平均直接效应为非零，规范,自我效能感,和过去的行为对FH自我管理行为意图的影响。过去的行为对社会认知结构介导的意图也存在非零平均间接影响。
结论：研究结果为支持所提出的模型提供了证据，并强调了个人，规范性，与能力相关的信念和过去的经验作为执行FH自我管理行为的意图的独特相关性。该模型可能预示着可能成为行为干预目标的潜在结构，以促进参与FH自我管理行为。
