Abstract：
Galleria mellonella larvae are a popular and simple model organism for infectious disease research. Last instar larvae can be purchased inexpensively from commercial suppliers and infected with Cryptococcus. Injection into the proleg of larvae results in systemic infections. Larvae may then be monitored for survival or homogenized to determine fungal burden. Fixation of infected larvae produces samples suitable for histological staining and analysis.
摘要：
云形藻幼虫是一种流行的简单的传染病研究模式生物。最后龄幼虫可以从商业供应商廉价地购买并感染隐球菌。向幼虫的前肢注射会导致全身性感染。然后可以监测幼虫的存活或匀浆以确定真菌负荷。固定受感染的幼虫产生适合于组织学染色和分析的样品。
