METHODS: An observational, cross sectional survey study was employed.
METHODS: 1042 active females (aged 18-65) completed a comprehensive screening questionnaire and 887 (85 % compliance) provided a fingerprick blood sample for haemoglobin (Hb) concentration measurement. Women that presented as anaemic (defined as a [Hb] < 120 g/L) or deemed to be at risk of iron deficiency (120 < [Hb] < 130 g/L) were asked to complete follow-up blood tests to screen for iron studies.
RESULTS: Average [Hb] was 134.2 ± 12.1 g/L, with 94 individuals considered anaemic (10.6 %). Of the sample, 104 underwent follow-up blood tests; 51 (~49 %) presented with iron deficiency (defined as ferritin <30 μg/L). Based on survey responses, 274 (30.9 %) participants were determined to have heavy menstrual bleeding. Those presenting with heavy menstrual bleeding were younger, exercised fewer hours per week, and were more likely to have a history of iron deficiency or anaemia (all p < 0.05). Participants reporting a history of anaemia or iron deficiency were more likely to have heavy menstrual bleeding (anaemia: 39.7 %; iron deficiency; 36.9 %; both p < 0.05).
CONCLUSIONS: In this cohort of exercising females of reproductive age, the prevalence of anaemia was 10.6 %. There is a strong association between heavy menstrual bleeding and a self-reported history of iron deficiency and anaemia. Greater awareness of heavy menstrual bleeding and its relationship with iron deficiency and anaemia is needed in this population. Non-invasive screening should be conducted to raise awareness and further understand the associated risk factors and symptomatology.
方法:观察性,采用横断面调查研究。
方法:1042名活跃女性(18-65岁)完成了全面的筛查问卷,887名(85%的依从性)提供了用于血红蛋白(Hb)浓度测量的手指刺血样本。要求表现为贫血(定义为[Hb]<120g/L)或被认为有铁缺乏风险(120<[Hb]<130g/L)的妇女完成后续血液测试以筛选铁研究。
结果:平均[Hb]为134.2±12.1g/L,94人认为贫血(10.6%)。在样本中,104例接受了随访血液检查;51例(约49%)表现为缺铁(定义为铁蛋白<30μg/L)。根据调查答复,274名(30.9%)参与者被确定为月经大量出血。那些出现大量月经出血的人更年轻,每周锻炼更少的时间,并且更有可能有缺铁或贫血史(均p<0.05)。报告有贫血或缺铁史的参与者更有可能有严重的月经出血(贫血:39.7%;缺铁;36.9%;两者均p<0.05)。
结论:在这个育龄女性锻炼队列中,贫血的患病率为10.6%.大量月经出血与自我报告的缺铁和贫血病史之间存在很强的关联。在这一人群中,需要更多地了解大量月经出血及其与缺铁和贫血的关系。应进行非侵入性筛查,以提高认识并进一步了解相关的危险因素和症状。