Mesh : Mast Cells / immunology Animals Intestinal Mucosa / immunology parasitology Humans Homeostasis / immunology Helminthiasis / immunology parasitology Epithelial Cells / immunology Mice

来  源:   DOI:10.1016/j.immuni.2024.04.020

Abstract:
The intestinal epithelium interacts with immune cells to support tissue homeostasis and coordinate responses against pathogens. In this issue of Immunity, Yang et al. unveil a central role for mast cell-epithelial cell interactions in orchestrating protective type 2 immune responses following intestinal helminth infection.
摘要:
肠上皮与免疫细胞相互作用以支持组织稳态并协调针对病原体的反应。在本期的豁免权中,Yangetal.揭示了肥大细胞-上皮细胞相互作用在协调肠道蠕虫感染后的保护性2型免疫反应中的核心作用。
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