PDF(Pubmed)
Abstract：
UNASSIGNED: Peritoneal dialysis (PD) is a major renal replacement therapy modality for patients with end-stage kidney disease (ESKD) worldwide. As poor self-care of PD patients could lead to serious complications, including peritonitis, exit-site infection, technique failure, and death; several nurse-based educational interventions have been introduced. However, these interventions varied and have been supported by small-scale studies so the effectiveness of nurse-based educational interventions on clinical outcomes of PD patients has been inconclusive.
UNASSIGNED: To evaluate the effectiveness of nurse-based education interventions in PD patients.
UNASSIGNED: A systematic review and meta-analysis of Randomized Controlled Trials (RCTs).
UNASSIGNED: We performed a systematic search using PubMed, Embase, and CENTRAL up to December 31, 2021. Selection criteria included Randomized Controlled Trials (RCTs) relevant to nurse-based education interventions in ESKD patients with PD in the English language. The meta-analyses were conducted using a random-effects model to evaluate the summary outcomes of peritonitis, PD-related infection, mortality, transfer to hemodialysis, and quality of life (QoL).
UNASSIGNED: From 9,816 potential studies, 71 theme-related abstracts were selected for further full-text articles screening against eligibility criteria. As a result, eleven studies (1,506 PD patients in seven countries) were included in our systematic review. Of eleven studies, eight studies (1,363 PD patients in five countries) were included in the meta-analysis. Sleep QoL in the intervention group was statistically significantly higher than control (mean difference = 12.76, 95% confidence intervals 5.26-20.27). There was no difference between intervention and control groups on peritonitis, PD-related infection, HD transfer, and overall QoL.
UNASSIGNED: Nurse-based educational interventions could help reduce some PD complications, of which only the sleep QoL showed statistically significant improvement. High-quality evidence on the nurse-based educational interventions was limited and more RCTs are needed to provide more robust outcomes.
UNASSIGNED: Nurse-based educational interventions showed promising sleep quality improvement and potential peritonitis risk reduction among PD patients.
UNASSIGNED: To evaluate the effectiveness of nurse-based education interventions in PD patients.
UNASSIGNED: A systematic review and meta-analysis of Randomized Controlled Trials (RCTs).
UNASSIGNED: We performed a systematic search using PubMed, Embase, and CENTRAL up to December 31, 2021. Selection criteria included Randomized Controlled Trials (RCTs) relevant to nurse-based education interventions in ESKD patients with PD in the English language. The meta-analyses were conducted using a random-effects model to evaluate the summary outcomes of peritonitis, PD-related infection, mortality, transfer to hemodialysis, and quality of life (QoL).
UNASSIGNED: From 9,816 potential studies, 71 theme-related abstracts were selected for further full-text articles screening against eligibility criteria. As a result, eleven studies (1,506 PD patients in seven countries) were included in our systematic review. Of eleven studies, eight studies (1,363 PD patients in five countries) were included in the meta-analysis. Sleep QoL in the intervention group was statistically significantly higher than control (mean difference = 12.76, 95% confidence intervals 5.26-20.27). There was no difference between intervention and control groups on peritonitis, PD-related infection, HD transfer, and overall QoL.
UNASSIGNED: Nurse-based educational interventions could help reduce some PD complications, of which only the sleep QoL showed statistically significant improvement. High-quality evidence on the nurse-based educational interventions was limited and more RCTs are needed to provide more robust outcomes.
UNASSIGNED: Nurse-based educational interventions showed promising sleep quality improvement and potential peritonitis risk reduction among PD patients.
摘要：
■腹膜透析（PD）是全球终末期肾病（ESKD）患者的主要肾脏替代治疗方式。由于PD患者自理能力差可能导致严重的并发症，包括腹膜炎,出口部位感染,技术失败，和死亡；已经引入了几种基于护士的教育干预措施。然而,这些干预措施各不相同,并得到了小规模研究的支持,因此以护士为基础的教育干预对PD患者临床结局的有效性尚无定论.
■评估以护士为基础的教育干预对PD患者的有效性。
■随机对照试验（RCT）的系统评价和荟萃分析。
■我们使用PubMed进行了系统搜索，Embase,和中央至2021年12月31日。选择标准包括以英语为基础的ESKDPD患者的基于护士的教育干预相关的随机对照试验（RCTs）。使用随机效应模型进行meta分析，以评估腹膜炎的总结结果。PD相关感染,死亡率,转入血液透析,和生活质量(QoL)。
■来自9,816项潜在研究，选择了71篇与主题相关的摘要，用于根据资格标准进行进一步的全文文章筛选。因此,11项研究(7个国家的1,506例PD患者)纳入我们的系统评价。在11项研究中，8项研究(5个国家的1,363例PD患者)纳入荟萃分析.干预组睡眠QoL显著高于对照组(均差=12.76,95%置信区间5.26-20.27)。干预组和对照组在腹膜炎方面无差异。PD相关感染,高清传输,和整体QoL。
■基于护士的教育干预措施可以帮助减少某些PD并发症，其中只有睡眠QoL显示出统计学上的显着改善。基于护士的教育干预措施的高质量证据有限，需要更多的随机对照试验来提供更可靠的结果。
■基于护士的教育干预显示PD患者睡眠质量有希望改善，腹膜炎风险有可能降低。
■评估以护士为基础的教育干预对PD患者的有效性。
■随机对照试验（RCT）的系统评价和荟萃分析。
■我们使用PubMed进行了系统搜索，Embase,和中央至2021年12月31日。选择标准包括以英语为基础的ESKDPD患者的基于护士的教育干预相关的随机对照试验（RCTs）。使用随机效应模型进行meta分析，以评估腹膜炎的总结结果。PD相关感染,死亡率,转入血液透析,和生活质量(QoL)。
■来自9,816项潜在研究，选择了71篇与主题相关的摘要，用于根据资格标准进行进一步的全文文章筛选。因此,11项研究(7个国家的1,506例PD患者)纳入我们的系统评价。在11项研究中，8项研究(5个国家的1,363例PD患者)纳入荟萃分析.干预组睡眠QoL显著高于对照组(均差=12.76,95%置信区间5.26-20.27)。干预组和对照组在腹膜炎方面无差异。PD相关感染,高清传输,和整体QoL。
■基于护士的教育干预措施可以帮助减少某些PD并发症，其中只有睡眠QoL显示出统计学上的显着改善。基于护士的教育干预措施的高质量证据有限，需要更多的随机对照试验来提供更可靠的结果。
■基于护士的教育干预显示PD患者睡眠质量有希望改善，腹膜炎风险有可能降低。
