Drying enhances the antioxidant activity of Allium mongolicum Regel through the phenylpropane and AA-MA pathway as shown by metabolomics.

如代谢组学所示 ， 干燥通过苯丙烷和 AA - MA 途径增强了沙葱的抗氧化活性。

• 影响指数: 6.443
• 发表时间: 2024 Jun 30
• 来源期刊: Food Chem X
• DOI: 10.1016/j.fochx.2024.101436
• PMID: 38742170
• 文章类型: Journal Article
• 作者列表: Liu W,Yu A,Xie Y,Yao H,Sun C,Gao H,He J,Ao C,Tang D

关键词: Antioxidant activity; Metabolomics; Phytochemicals; Primary metabolites; Secondary metabolites

Abstract

Fresh Allium mongolicum Regel (FA) and dried A. mongolicum Regel (DA) are significantly different in antioxidant activity. However, the relevant mechanisms have not yet been explored. We evaluated the antioxidant activities of two varieties of FA and DA and characterized their metabolites using targeted metabolomics. The effect of different metabolites on the antioxidant activity of A. mongolicum Regel was investigated by multivariate analysis. A total of 713 metabolites were detected in all samples. Pearson correlation analysis demonstrated that the key primary metabolites were directly and significantly correlated with the total phenolic content (TPC) and total flavonoid content (TFC), while the secondary metabolites were directly correlated with antioxidant activity. The higher antioxidant activity of DA may be mainly attributed to the higher TPC and TFC. This study revealed the potential mechanism by which drying enhances the antioxidant activity of A. mongolicum Regel.

摘要

新鲜沙葱（FA）和干燥沙葱（DA）的抗氧化活性显着不同。然而,相关机制尚未探索。我们评估了两种FA和DA的抗氧化活性，并使用靶向代谢组学对其代谢产物进行了表征。通过多变量分析研究了不同代谢产物对蒙古曲霉抗氧化活性的影响。在所有样品中共检测到713种代谢物。Pearson相关分析表明，关键初级代谢产物与总酚含量（TPC）和总黄酮含量（TFC）直接且显著相关。次生代谢产物与抗氧化活性直接相关。DA较高的抗氧化活性可能主要归因于较高的TPC和TFC。这项研究揭示了干燥增强蒙古曲霉抗氧化活性的潜在机理。