关键词: Eye Infectious diseases Medical management

Mesh : Humans Female Chorioretinitis / drug therapy diagnosis parasitology Toxoplasmosis, Ocular / diagnosis drug therapy complications Toxoplasma / isolation & purification Adult Multimodal Imaging Vasculitis / drug therapy diagnosis complications Visual Acuity Clindamycin / therapeutic use administration & dosage Tomography, Optical Coherence Anti-Bacterial Agents / therapeutic use

来  源:   DOI:10.1136/bcr-2022-253286

Abstract:
A woman in her late 30s presented with sudden diminution of vision, redness and pain in the right eye (OD) of 10 days\' duration. Best corrected visual acuity (BCVA) was 20/160 in OD and 20/20 in the left eye (OS). Anterior segment of OD showed keratic precipitates, flare 3+, cells 2+ and a festooned pupil. Vitreous haze and cells were seen in OD. Frosted branch angiitis (FBA) was seen in all quadrants in OD and old Toxoplasma scar was seen in both eyes. Serum toxoplasma immunoglobulin G (IgG) was positive and IgM negative, and PCR of an aqueous humour sample was negative for Toxoplasma She was diagnosed with toxoplasa retinochoroiditis in OD and treated with intravitreal clindamycin injections, oral anti-Toxoplasma antibiotics and steroids. Three months later, her BCVA in OD was 20/40 with resolving inflammation. She presented 2 months later with a new focus of retinochoroiditis without FBA and an old Toxoplasma scar.
摘要:
一名30多岁的妇女视力突然下降,右眼发红和疼痛(OD)10天的持续时间。最佳矫正视力(BCVA)OD为20/160,左眼(OS)为20/20。OD的前段显示有角质沉淀,耀斑3+,细胞2+和一个花彩的瞳孔。在OD中可见玻璃体混浊和细胞。在OD的所有象限中均可见结霜分支血管炎(FBA),双眼均可见旧的弓形虫疤痕。血清弓形虫免疫球蛋白G(IgG)阳性,IgM阴性,房水样本的PCR对弓形虫呈阴性。她被诊断患有OD的弓形虫视网膜脉络膜炎,并接受玻璃体内注射克林霉素治疗,口服抗弓形虫抗生素和类固醇。三个月后,她的BCVA的OD为20/40,炎症消退。2个月后,她出现了没有FBA和旧弓形虫疤痕的视网膜脉络膜炎的新病灶。
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