关键词: COPD Japan airflow obstruction epidemiology prevalence real-world data

Mesh : Humans Pulmonary Disease, Chronic Obstructive / epidemiology diagnosis physiopathology Male Female Japan / epidemiology Middle Aged Prevalence Aged Adult Spirometry Forced Expiratory Volume Databases, Factual Lung / physiopathology Vital Capacity Smoking / epidemiology adverse effects Predictive Value of Tests Severity of Illness Index

来  源:   DOI:10.2147/COPD.S450270   PDF(Pubmed)

Abstract:
UNASSIGNED: The prevalence of airflow obstruction in Japan is 3.8%-16.9%. This epidemiological study based on a large database aimed to reassess the prevalence of airflow obstruction in Japan and the diagnosis rate of chronic obstructive pulmonary disease (COPD).
UNASSIGNED: We used data regarding claims from the health insurance union and health checkups provided by JMDC. The present study included a subgroup of individuals aged ≥40 years who underwent health checkups involving spirometry between January and December 2019. The study endpoints were the prevalence of airflow obstruction, COPD diagnosis rate, disease stage, and respiratory function test results.
UNASSIGNED: Among 102,190 participants, 4113 (4.0%) had airflow obstruction. The prevalence of airflow obstruction was 5.3% in men and 2.1% in women. Among the study population, 6.8% were current smokers, while 3.4% were never or former smokers. Additionally, the prevalence of COPD increased with age. Approximately 8.4% of participants with airflow obstruction were diagnosed with COPD. Regarding the COPD diagnosis status, participants with airflow obstruction who were diagnosed with COPD were at a more advanced stage than those not diagnosed. Finally, patients diagnosed with COPD had significantly lower FEV1/FVC and FEV1 (p < 0.0001; Wilcoxon rank sum test).
UNASSIGNED: The epidemiological study based on a large database determined the COPD diagnosis rate related to airflow obstruction. The COPD diagnosis rate was extremely low among individuals who underwent health checkups, indicating the need for increased awareness about this medical condition. Moreover, primary care physicians should identify patients with suspected COPD and collaborate with pulmonologists to facilitate the early detection of COPD and enhance the COPD diagnosis rate.
摘要:
日本气流阻塞的患病率为3.8%-16.9%。这项基于大型数据库的流行病学研究旨在重新评估日本气流阻塞的患病率和慢性阻塞性肺疾病(COPD)的诊断率。
我们使用了JMDC提供的有关健康保险联盟索赔和健康检查的数据。本研究包括一组年龄≥40岁的个体,他们在2019年1月至12月期间接受了包括肺活量测定的健康检查。研究终点是气流阻塞的患病率,COPD诊断率,疾病阶段,和呼吸功能测试结果。
在102,190名参与者中,4113(4.0%)有气流阻塞。男性气流阻塞的患病率为5.3%,女性为2.1%。在研究人群中,6.8%是目前的吸烟者,而3.4%的人从未或以前吸烟者。此外,COPD患病率随年龄增长而增加.大约8.4%的气流阻塞患者被诊断为COPD。关于COPD的诊断状况,被诊断为COPD的气流阻塞参与者比未被诊断的参与者处于更晚期.最后,诊断为COPD的患者FEV1/FVC和FEV1显著降低(p<0.0001;Wilcoxon秩和检验).
基于大型数据库的流行病学研究确定了与气流阻塞相关的COPD诊断率。在接受健康体检的人群中,COPD诊断率极低,表明需要提高对这种医疗状况的认识。此外,初级保健医师应确定疑似COPD患者,并与肺科医师合作,以促进COPD的早期发现并提高COPD的诊断率.
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