关键词: angiogenesis bioactive dressing inflammation plastic surgery skin stem cells wound healing wounds

来  源:   DOI:10.3390/jcm13092488   PDF(Pubmed)

Abstract:
Wound management presents a significant global challenge, necessitating a comprehensive understanding of wound care products and clinical expertise in selecting dressings. Bioactive dressings (BD) represent a diverse category of dressings, capable of influencing wound healing through various mechanisms. These dressings, including honey, hyaluronic acid, collagen, alginates, and polymers enriched with polyhexamethylene biguanide, chitin, and chitosan derivatives, create a conducive environment for healing, promoting moisture balance, pH regulation, oxygen permeability, and fluid management. Interactive dressings further enhance targeted action by serving as substrates for bioactive agents. The continuous evolution of BDs, with new products introduced annually, underscores the need for updated knowledge in wound care. To facilitate dressing selection, a practical algorithm considers wound exudate, infection probability, and bleeding, guiding clinicians through the process. This algorithm aims to optimize wound care by ensuring the appropriate selection of BDs tailored to individual patient needs, ultimately improving outcomes in wound management.
摘要:
伤口管理提出了重大的全球挑战,需要全面了解伤口护理产品和选择敷料的临床专业知识。生物活性敷料(BD)代表了不同类别的敷料,能够通过各种机制影响伤口愈合。这些敷料,包括蜂蜜,透明质酸,胶原蛋白,藻酸盐,和富含聚六亚甲基双胍的聚合物,甲壳素,和壳聚糖衍生物,创造一个有利于愈合的环境,促进水分平衡,pH调节,透氧性,和流体管理。交互式敷料通过充当生物活性剂的底物而进一步增强靶向作用。BD的不断发展,随着每年推出的新产品,强调需要更新伤口护理知识。为了方便选择敷料,一个实用的算法考虑伤口渗出物,感染概率,流血,指导临床医生完成这一过程。该算法旨在通过确保适当选择适合个体患者需求的BD来优化伤口护理。最终改善伤口管理的结果。
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