METHODS: Some preschoolers with these characteristics randomly took this product, containing lactoferrin, dipotassium glycyrrhizinate, carboxymethyl-beta-glucan, and vitamins C and D3 (Saflovir), two sprays per nostril twice daily for 3 months. Other children were randomly treated only with standard therapy. Outcomes included the number of RIs and wheezing episodes, use of medications, and severity of clinical manifestations.
RESULTS: Preschoolers treated add-on with this multicomponent product experienced fewer RIs and used fewer beta-2 agonists than untreated children (P = 0.01 and 0.029, respectively).
CONCLUSIONS: This preliminary study demonstrated that a multicomponent product, administered add-on as a nasal spray, could reduce the incidence of RIs and use of symptomatic drugs for relieving wheezing in children.
方法:一些具有这些特征的学龄前儿童随机服用了该产品,含有乳铁蛋白,甘草酸二钾,羧甲基-β-葡聚糖,和维生素C和D3(Saflovir),每个鼻孔两次喷雾,每天两次,持续3个月。其他儿童仅随机接受标准治疗。结果包括RI的数量和喘息发作,使用药物,和临床表现的严重程度。
结果:使用这种多组分产品进行附加治疗的学龄前儿童比未经治疗的儿童经历更少的RI,并且使用更少的β-2激动剂(分别为P=0.01和0.029)。
结论:这项初步研究表明,多组分产品,作为鼻喷雾剂添加,可以减少RIs的发生率和使用对症药物缓解儿童喘息。