Abstract：
BACKGROUND: This study interrogates infection related data in the Burns Registry of Australia and New Zealand (BRANZ), to examine associations of multi-drug resistant organisms (MDROs) and blood stream infection (BSI).
METHODS: Data between July 2016 and June 2021 were analysed to determine prevalence, risk factors and outcomes associated with BSIs and MDROs: Methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE), carbapenem-resistant Pseudomonas spp. (CRP), and carbapenem-resistant Enterobacter (CRE). Data completeness and value for quality improvement activity were assessed.
RESULTS: We found a low incidence (3.4%) of the resistant organisms of interest, and no change over the study period. Fequency varied between services and increased with age and size of burn. MRSA was the commonest organism in all age groups. A positive BSI result occurred in 1.6% of patients (12.1% of cultures taken) at a median time of 10.2 days post injury. Free text identification of organisms was inconsistently documented.
CONCLUSIONS: The low rate and patterns of acquisition of MDROs of interest and BSIs is comparable with reports from countries with low incidence of massive burns. Wider adoption of a standardized laboratory reporting framework would help realise the potential of clinical quality registries to provide data which supports evidence based infection prevention initiatives.
METHODS: Data between July 2016 and June 2021 were analysed to determine prevalence, risk factors and outcomes associated with BSIs and MDROs: Methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE), carbapenem-resistant Pseudomonas spp. (CRP), and carbapenem-resistant Enterobacter (CRE). Data completeness and value for quality improvement activity were assessed.
RESULTS: We found a low incidence (3.4%) of the resistant organisms of interest, and no change over the study period. Fequency varied between services and increased with age and size of burn. MRSA was the commonest organism in all age groups. A positive BSI result occurred in 1.6% of patients (12.1% of cultures taken) at a median time of 10.2 days post injury. Free text identification of organisms was inconsistently documented.
CONCLUSIONS: The low rate and patterns of acquisition of MDROs of interest and BSIs is comparable with reports from countries with low incidence of massive burns. Wider adoption of a standardized laboratory reporting framework would help realise the potential of clinical quality registries to provide data which supports evidence based infection prevention initiatives.
摘要：
背景：这项研究询问了澳大利亚和新西兰烧伤登记处（BRANZ）的感染相关数据，检查多药耐药菌（MDRO）和血流感染（BSI）的关联。
方法：分析了2016年7月至2021年6月的数据，以确定患病率，与BSI和MDRO相关的危险因素和结局：耐甲氧西林金黄色葡萄球菌（MRSA），耐万古霉素肠球菌(VRE),耐碳青霉烯类假单胞菌属。（CRP），和耐碳青霉烯类肠杆菌(CRE)。评估了数据完整性和质量改进活动的价值。
结果：我们发现目标抗性生物的发生率较低（3.4％），在研究期间没有变化。服务之间的费用有所不同，并随年龄和烧伤大小而增加。MRSA是所有年龄组中最常见的生物。在损伤后10.2天的中位时间,1.6%的患者(所采取的培养物的12.1%)出现阳性BSI结果。生物的自由文本识别记录不一致。
结论：感兴趣的MDRO和BSI的获取率和模式较低，与大量烧伤发生率较低的国家的报告相当。更广泛地采用标准化的实验室报告框架将有助于实现临床质量登记册的潜力，以提供数据来支持基于证据的感染预防计划。
方法：分析了2016年7月至2021年6月的数据，以确定患病率，与BSI和MDRO相关的危险因素和结局：耐甲氧西林金黄色葡萄球菌（MRSA），耐万古霉素肠球菌(VRE),耐碳青霉烯类假单胞菌属。（CRP），和耐碳青霉烯类肠杆菌(CRE)。评估了数据完整性和质量改进活动的价值。
结果：我们发现目标抗性生物的发生率较低（3.4％），在研究期间没有变化。服务之间的费用有所不同，并随年龄和烧伤大小而增加。MRSA是所有年龄组中最常见的生物。在损伤后10.2天的中位时间,1.6%的患者(所采取的培养物的12.1%)出现阳性BSI结果。生物的自由文本识别记录不一致。
结论：感兴趣的MDRO和BSI的获取率和模式较低，与大量烧伤发生率较低的国家的报告相当。更广泛地采用标准化的实验室报告框架将有助于实现临床质量登记册的潜力，以提供数据来支持基于证据的感染预防计划。
