关键词: Balloon dilatation Dyspnea index Short form healthy survey Subglottic stenosis

Mesh : Humans Laryngostenosis / therapy Quality of Life Male Female Dyspnea / etiology therapy Middle Aged Dilatation / methods Aged Patient Reported Outcome Measures Adult Treatment Outcome Sweden

来  源:   DOI:10.1007/s00405-024-08667-0   PDF(Pubmed)

Abstract:
OBJECTIVE: An accurate diagnosis and proper treatment plan are required to restore an adequate patent airway in fibrotic subglottic stenosis (SGS). Currently, the definitive treatment entails single-stage balloon dilatation with steroid injections. The primary aim was to evaluate successful airway restoration and general quality of life in cases with SGS in northern Sweden using robust patient reported outcomes.
METHODS: All participants with need of surgical treatment due to SGS that had been referred to the department of otorhinolaryngology, University Hospital of Umeå from September 2020 to August 2023 was included. Exclusion criteria included malignant, extrathoracic or cartilaginous cause, age < 18 years, or incompetent to sign consent documents. We assessed the patient-reported outcome measures pre- as well as 3 months postoperatively.
RESULTS: Of the 40 cases fulfilling the eligibility criteria\'s, 33 cases completed the Dyspnea index (DI) and the short form health survey (SF-36) pre- as well as 3 months post-operatively. Receiver operating characteristics showed significant improvement in DI as well as in SF 36 scores post-operatively.
CONCLUSIONS: Evaluation of balloon dilatation in SGS in this cohort follow-up analysis shows clear improvement in patient quality of life using robust PROM 3 months postoperatively, ensuring the use of a safe and well-tolerated procedure.
摘要:
目的:需要准确的诊断和适当的治疗计划,才能在纤维化声门下狭窄(SGS)中恢复足够的气道通畅。目前,最终的治疗需要单阶段球囊扩张与类固醇注射。主要目的是使用可靠的患者报告结果评估瑞典北部SGS病例的成功气道恢复和一般生活质量。
方法:所有因SGS转诊耳鼻喉科而需要手术治疗的参与者,包括2020年9月至2023年8月的于默奥大学医院。排除标准包括恶性,胸外或软骨原因,年龄<18岁,或者没有能力签署同意书。我们评估了患者报告的术前和术后3个月的结果指标。
结果:在符合资格标准的40个案例中,33例患者在手术前和术后3个月完成了呼吸困难指数(DI)和短期健康调查(SF-36)。接收器的工作特征显示,术后DI和SF36得分均有显着改善。
结论:在本队列随访分析中,SGS对球囊扩张的评估显示,术后3个月使用稳健的PROM可明显改善患者的生活质量,确保使用安全和耐受性良好的程序。
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