Abstract：
OBJECTIVE: The purpose of this systematic review is to present and compare results from studies that have been using autologous tissue for POP repair.
METHODS: Systematic review was done according to the Cochrane Handbook for Systematic Reviews. We aimed to retrieve reports of published and ongoing studies on the efficacy and safety of autologous tissue in vaginal vault prolapse repair. The databases searched were MEDLINE (PubMed interface), Scopus, Cohrane Central Register of Controlled Trials (CENTRAL) and ClinicalTrials.gov.
RESULTS: The success rate varied among studies. In fascia-lata group success rate reports varied from 83 to a 100%, with a median follow-up from 12 to 52 months among studies. Rectus fascia reported success rates from 87 to a 100% with a follow-up of 12 months to longest of 98 months.
CONCLUSIONS: Autologous tissues show satisfying outcomes in terms of safety and efficacy. Sacrocolpopexy procedure with fascia lata has better outcome in term of treatment of prolapse. Harvesting place on lateral side of buttock has more complications in comparison with rectus fascia but size of the graft can be wider in fascia-lata group.
METHODS: Systematic review was done according to the Cochrane Handbook for Systematic Reviews. We aimed to retrieve reports of published and ongoing studies on the efficacy and safety of autologous tissue in vaginal vault prolapse repair. The databases searched were MEDLINE (PubMed interface), Scopus, Cohrane Central Register of Controlled Trials (CENTRAL) and ClinicalTrials.gov.
RESULTS: The success rate varied among studies. In fascia-lata group success rate reports varied from 83 to a 100%, with a median follow-up from 12 to 52 months among studies. Rectus fascia reported success rates from 87 to a 100% with a follow-up of 12 months to longest of 98 months.
CONCLUSIONS: Autologous tissues show satisfying outcomes in terms of safety and efficacy. Sacrocolpopexy procedure with fascia lata has better outcome in term of treatment of prolapse. Harvesting place on lateral side of buttock has more complications in comparison with rectus fascia but size of the graft can be wider in fascia-lata group.
摘要：
目的：本系统综述的目的是介绍和比较使用自体组织进行POP修复的研究结果。
方法：根据Cochrane系统评价手册进行系统评价。我们旨在检索已发表和正在进行的有关自体组织在阴道穹窿脱垂修复中的疗效和安全性的研究报告。搜索的数据库是MEDLINE（PubMed接口），Scopus,Cohrane中央对照试验登记册（CENTRAL）和ClinicalTrials.gov。
结果：各研究的成功率各不相同。在筋膜-lata组中，成功率报告从83到100％不等，研究中的中位随访时间为12至52个月。直肌筋膜报告成功率从87％到100％，随访12个月至最长98个月。
结论：自体组织在安全性和有效性方面显示出令人满意的结果。在脱垂的治疗方面，采用阔筋膜下的膀胱切除术具有更好的效果。与直肌筋膜相比，臀部外侧的收获部位有更多的并发症，但筋膜-筋膜组的移植物大小可以更宽。
方法：根据Cochrane系统评价手册进行系统评价。我们旨在检索已发表和正在进行的有关自体组织在阴道穹窿脱垂修复中的疗效和安全性的研究报告。搜索的数据库是MEDLINE（PubMed接口），Scopus,Cohrane中央对照试验登记册（CENTRAL）和ClinicalTrials.gov。
结果：各研究的成功率各不相同。在筋膜-lata组中，成功率报告从83到100％不等，研究中的中位随访时间为12至52个月。直肌筋膜报告成功率从87％到100％，随访12个月至最长98个月。
结论：自体组织在安全性和有效性方面显示出令人满意的结果。在脱垂的治疗方面，采用阔筋膜下的膀胱切除术具有更好的效果。与直肌筋膜相比，臀部外侧的收获部位有更多的并发症，但筋膜-筋膜组的移植物大小可以更宽。
