Abstract：
OBJECTIVE: The fit and optical performance of a scleral lens is affected by the alignment of the landing zone with the underlying ocular surface. The aim of this research was to quantify the effect of landing zone toricity upon scleral lens fitting characteristics (rotation and decentration) and optics (lens flexure) during short-term wear.
METHODS: Scleral lenses with nominal landing zone toricities of 0, 100, 150 and 200 μm were worn in a randomised order by 10 young healthy participants (mean [SD] 24 [7] years) for 30 min, with other lens parameters held constant. Scleral toricity was quantified using a corneo-scleral profilometer, and lens flexure, rotation, and decentration were quantified using over-topography during lens wear. Repeated measures analyses were conducted as a function of landing zone toricity and residual scleral toricity (the difference between scleral and lens toricity) for eyes with \'low\' magnitude scleral toricity (mean: 96 μm) and \'high\' magnitude scleral toricity (mean: 319 μm).
RESULTS: Toric landing zones significantly reduced lens flexure (by 0.37 [0.21] D, p < 0.05) and lens rotation (by 20 [24]°, p < 0.05) compared with a spherical landing zone. Horizontal and vertical lens decentration did not vary significantly with landing zone toricity. These trends for flexure, rotation, and decentration were also observed for eyes with \'low\' and \'high\' magnitude scleral toricity as a function of residual scleral toricity.
CONCLUSIONS: Landing zones with 100-200 μm toricity significantly reduced lens flexure (by ~62%) and rotation (by ~77%) but not horizontal or vertical lens decentration, compared with a spherical landing zone, when controlling for other confounding variables. The incorporation of a toric landing zone, even for eyes with lower magnitude scleral toricity (~100 μm), may be beneficial, particularly for front surface optical designs.
METHODS: Scleral lenses with nominal landing zone toricities of 0, 100, 150 and 200 μm were worn in a randomised order by 10 young healthy participants (mean [SD] 24 [7] years) for 30 min, with other lens parameters held constant. Scleral toricity was quantified using a corneo-scleral profilometer, and lens flexure, rotation, and decentration were quantified using over-topography during lens wear. Repeated measures analyses were conducted as a function of landing zone toricity and residual scleral toricity (the difference between scleral and lens toricity) for eyes with \'low\' magnitude scleral toricity (mean: 96 μm) and \'high\' magnitude scleral toricity (mean: 319 μm).
RESULTS: Toric landing zones significantly reduced lens flexure (by 0.37 [0.21] D, p < 0.05) and lens rotation (by 20 [24]°, p < 0.05) compared with a spherical landing zone. Horizontal and vertical lens decentration did not vary significantly with landing zone toricity. These trends for flexure, rotation, and decentration were also observed for eyes with \'low\' and \'high\' magnitude scleral toricity as a function of residual scleral toricity.
CONCLUSIONS: Landing zones with 100-200 μm toricity significantly reduced lens flexure (by ~62%) and rotation (by ~77%) but not horizontal or vertical lens decentration, compared with a spherical landing zone, when controlling for other confounding variables. The incorporation of a toric landing zone, even for eyes with lower magnitude scleral toricity (~100 μm), may be beneficial, particularly for front surface optical designs.
摘要：
目的：巩膜晶状体的贴合性和光学性能受着陆区与下方眼表对齐的影响。这项研究的目的是量化短期佩戴过程中着陆区环度对巩膜镜片拟合特性（旋转和偏心）和光学（镜片弯曲）的影响。
方法：10名年轻健康参与者（平均[SD]24[7]年）按随机顺序佩戴标称着陆区环度为0、100、150和200μm的巩膜镜片30分钟，与其他镜头参数保持恒定。使用角膜巩膜轮廓测定仪对巩膜的环度进行量化，和透镜弯曲，旋转,使用镜片佩戴过程中的过度形貌对偏心进行量化。对于“低”级巩膜复曲面(平均:96μm)和“高”级巩膜复曲面(平均:319μm)的眼睛,根据着陆区复曲面和残余巩膜复曲面(巩膜和晶状体复曲面之间的差异)进行重复测量分析。
结果：复曲面着陆区显着降低了晶状体弯曲（0.37[0.21]D，p<0.05)和透镜旋转(20[24]°，p<0.05）与球形着陆区相比。水平和垂直透镜偏心随着陆区的复曲面没有显着变化。这些弯曲的趋势，旋转,对于具有“低”和“高”量级巩膜复光度的眼睛，也观察到了偏心，这是残余巩膜复光度的函数。
结论：具有100-200μm环度的着陆区显著降低了晶状体弯曲（约62%）和旋转（约77%），但没有降低水平或垂直的晶状体偏心，与球形着陆区相比，当控制其他混杂变量时。合并了复曲面着陆区，即使是巩膜环度较低(~100μm)的眼睛，可能是有益的，特别是前表面光学设计。
方法：10名年轻健康参与者（平均[SD]24[7]年）按随机顺序佩戴标称着陆区环度为0、100、150和200μm的巩膜镜片30分钟，与其他镜头参数保持恒定。使用角膜巩膜轮廓测定仪对巩膜的环度进行量化，和透镜弯曲，旋转,使用镜片佩戴过程中的过度形貌对偏心进行量化。对于“低”级巩膜复曲面(平均:96μm)和“高”级巩膜复曲面(平均:319μm)的眼睛,根据着陆区复曲面和残余巩膜复曲面(巩膜和晶状体复曲面之间的差异)进行重复测量分析。
结果：复曲面着陆区显着降低了晶状体弯曲（0.37[0.21]D，p<0.05)和透镜旋转(20[24]°，p<0.05）与球形着陆区相比。水平和垂直透镜偏心随着陆区的复曲面没有显着变化。这些弯曲的趋势，旋转,对于具有“低”和“高”量级巩膜复光度的眼睛，也观察到了偏心，这是残余巩膜复光度的函数。
结论：具有100-200μm环度的着陆区显著降低了晶状体弯曲（约62%）和旋转（约77%），但没有降低水平或垂直的晶状体偏心，与球形着陆区相比，当控制其他混杂变量时。合并了复曲面着陆区，即使是巩膜环度较低(~100μm)的眼睛，可能是有益的，特别是前表面光学设计。
