PDF(Pubmed)
Abstract：
Arterial pulse wave velocity (PWV) is recognized as a convenient method to assess peripheral vascular stiffness. This study explored the clinical characteristics of hand PWV (hPWV) and hand pulse transit time (hPTT) in healthy adults (sixty males = 42.4 ± 13.9 yrs; sixty-four females = 42.8 ± 13.9 yrs) voluntarily participated in this study. The arterial pulse waveform and the anatomical distance from the radial styloid process to the tip of the middle finger of both hands were recorded in the sitting position. The hPWV was calculated as the traversed distance divided by hPTT between those two points. Male subjects showed significantly greater hPWV, systolic blood pressure, and pulse pressure than age-matched female subjects, while the hPTT was not significantly different between genders. Multiple linear regression analysis showed that gender is a common determinant of hPWV and hPTT, and that age and heart rate (HR) were negatively correlated with hPWV and hPTT, respectively. We conclude that male subjects have greater hPWV than female subjects. Ageing is associated with decreased hPWV, while increased HR is associated with a smaller hPTT. The hPWV and hPTT might be used as non-invasive indices to characterise the ageing and arterial stiffness of peripheral blood vessels.
摘要：
动脉脉搏波速度（PWV）被认为是评估外周血管硬度的便捷方法。本研究探讨了自愿参加本研究的健康成年人（60名男性=42.4±13.9岁；64名女性=42.8±13.9岁）的手PWV（hPWV）和手脉搏传播时间（hPTT）的临床特征。记录坐位时的动脉脉搏波形和从桡骨茎突到双手中指尖端的解剖距离。将hPWV计算为遍历距离除以这两个点之间的hPTT。男性受试者表现出明显更大的hPWV，收缩压,和脉压比年龄匹配的女性受试者，而hPTT在性别之间没有显着差异。多元线性回归分析显示,性别是hPWV和hPTT的共同决定因素,年龄和心率（HR）与hPWV和hPTT呈负相关，分别。我们得出的结论是，男性受试者的hPWV高于女性受试者。老化与hPWV下降有关，而增加的HR与较小的hPTT相关。hPWV和hPTT可以用作非侵入性指标来表征外周血管的老化和动脉僵硬度。
