Abstract：
The aim of this study was to describe the natural history of incidental benign-appearing notochordal lesions of the skull base with specific attention to features that can make differentiation from low-grade chordoma more difficult, namely contrast uptake and bone erosion.
In this retrospective case series, the authors describe the clinical outcomes of 58 patients with incidental benign-appearing notochordal lesions of the clivus, including those with minor radiological features of bone erosion or contrast uptake.
All lesions remained stable during a median follow-up of almost 3 years. Thirty-seven (64%) patients underwent contrast-enhanced MRI; lesions in 14 (38%) of these patients exhibited minimal contrast enhancement. Twenty-seven (47%) patients underwent CT; lesions in 6 (22%) of these patients exhibited minimal bone erosion.
These data make the case for monitoring selected cases of benign-appearing notochordal lesions of the clivus in the first instance even when there is minor contrast uptake or minimal bone erosion.
In this retrospective case series, the authors describe the clinical outcomes of 58 patients with incidental benign-appearing notochordal lesions of the clivus, including those with minor radiological features of bone erosion or contrast uptake.
All lesions remained stable during a median follow-up of almost 3 years. Thirty-seven (64%) patients underwent contrast-enhanced MRI; lesions in 14 (38%) of these patients exhibited minimal contrast enhancement. Twenty-seven (47%) patients underwent CT; lesions in 6 (22%) of these patients exhibited minimal bone erosion.
These data make the case for monitoring selected cases of benign-appearing notochordal lesions of the clivus in the first instance even when there is minor contrast uptake or minimal bone erosion.
摘要：
目的：这项研究的目的是描述颅底偶然出现的良性脊索病变的自然史，特别注意可以使与低级别脊索瘤的区分更加困难的特征，即造影剂摄取和骨侵蚀。
方法：在本回顾性病例系列中，作者描述了58例偶然出现的良性脊索病变的临床结果，包括那些具有轻微骨侵蚀或造影剂吸收的放射学特征。
结果：在近3年的中位随访期间，所有病变均保持稳定。37例（64％）患者接受了对比增强MRI；这些患者中有14例（38％）的病变表现出最小的对比增强。27例（47％）患者接受了CT检查；这些患者中有6例（22％）的病变表现出轻微的骨侵蚀。
结论：这些数据使我们有理由首先监测选定的斜坡良性出现的脊索病变病例，即使有少量的对比剂摄取或轻微的骨侵蚀。
方法：在本回顾性病例系列中，作者描述了58例偶然出现的良性脊索病变的临床结果，包括那些具有轻微骨侵蚀或造影剂吸收的放射学特征。
结果：在近3年的中位随访期间，所有病变均保持稳定。37例（64％）患者接受了对比增强MRI；这些患者中有14例（38％）的病变表现出最小的对比增强。27例（47％）患者接受了CT检查；这些患者中有6例（22％）的病变表现出轻微的骨侵蚀。
结论：这些数据使我们有理由首先监测选定的斜坡良性出现的脊索病变病例，即使有少量的对比剂摄取或轻微的骨侵蚀。
