Abstract:
Postnasal drip (PND) is a common symptom encountered when evaluating subjects with sinonasal disease; it may be present without sinonasal disease or as a symptom of laryngopharyngeal reflux. It is postulated that PND stems from dysfunction of normal mucus clearance mechanisms; however, there is no definitive evidence elucidating an exact pathophysiology. Compounding the uncertainties surrounding PND is the lack of an objective assessment tool. Instead, treating physicians must rely on subjective complaints and investigators utilize validated patient-reported outcome instruments, such as the Sino-Nasal Outcome Test, to determine treatment efficacy. This review seeks to discuss the current understanding of PND and evidence regarding effective treatment strategies.
摘要:
鼻后滴漏(PND)是评估患有鼻窦疾病的受试者时遇到的常见症状;它可能在没有鼻窦疾病的情况下存在,也可能是咽喉反流(LPR)的症状。据推测,PND源于正常粘液清除机制的功能障碍,然而,没有明确的证据阐明确切的病理生理学。使PND周围的不确定性复杂化的是缺乏客观评估工具。相反,治疗医生必须依靠主观投诉,调查人员使用经过验证的患者报告结果工具,如中鼻结果测试(SNOT),以确定治疗效果。这篇综述旨在讨论当前对PND的理解以及有关有效治疗策略的证据。