奈坦色林,选择性 5 - HT2A 受体反向激动剂 ,减弱尼古丁戒断的方面 , 但不奖励小鼠。
关键词: 5-HT2A receptor Conditioned place preference Nelotanserin Nicotine Withdrawal
Mesh : Animals Substance Withdrawal Syndrome / drug therapy Reward Nicotine / pharmacology administration & dosage Male Mice, Inbred ICR Serotonin 5-HT2 Receptor Agonists / pharmacology Mice Dose-Response Relationship, Drug Tobacco Use Disorder / drug therapy Hyperalgesia / drug therapy chemically induced Receptor, Serotonin, 5-HT2A / metabolism drug effects Anxiety / drug therapy Nicotinic Agonists / pharmacology administration & dosage
来 源:
DOI:10.1016/j.bbr.2024.115019
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