OBJECTIVE: The aim of this study was to further corroborate the associations between CM, parenting style, and AD in a large representative sample of Chinese children and adolescents.
METHODS: Study subjects were derived from the Mental Health Survey for Children and Adolescents in Yunnan (MHSCAY), a population-based cross-sectional program.
METHODS: Individually matched case-control study design was adopted. Univariate and multivariate conditional binary logistic regression models were used to estimate the associations between CM, parenting style and AD. Dose-response trends were estimated using the Cochran-Armitage Chi-square test. A series of stratified analyses were conducted to explore effect modification on exposure-outcome association by some important features.
RESULTS: Totally we screened out 202 cases and 404 matched controls, with an age mean of 14.43 years. Conditional logistic regression models revealed that EA and a higher level of parental over-protection were significantly associated with increased risk of AD, with adjusted ORs of 3.39 (95 % CI: 2.07-5.56) and 1.93 (95 % CI: 1.28-2.90). Stratified analysis identified noticeable effect modification by sex, age, and whether the only child in the family.
CONCLUSIONS: Major findings of this study suggested that children and adolescents who had experienced EA or raised up by over-protective parents are at increased risk of AD. Targeted intervention measures should be developed and implemented for these high-risk youths.
目的:本研究的目的是进一步证实CM,父母教养方式,和AD在中国儿童和青少年的大量代表性样本中。
方法:研究对象来自云南省儿童和青少年心理健康调查(MHSCAY),基于人口的横断面计划。
方法:采用单独匹配的病例对照研究设计。单变量和多变量条件二元逻辑回归模型用于估计CM,父母教养方式和AD。使用Cochran-Armitage卡方检验估计剂量反应趋势。进行了一系列分层分析,以探索一些重要特征对暴露结果关联的影响修改。
结果:共筛选出202例病例和404个匹配对照,平均年龄14.43岁。条件logistic回归模型显示EA和更高水平的父母过度保护与AD风险增加显著相关。调整后的OR为3.39(95%CI:2.07-5.56)和1.93(95%CI:1.28-2.90)。分层分析确定了按性别划分的明显效应修饰,年龄,以及家庭中唯一的孩子。
结论:这项研究的主要发现表明,经历过EA或由过度保护的父母抚养长大的儿童和青少年患AD的风险增加。应针对这些高危青年制定和实施有针对性的干预措施。