Abstract：
BACKGROUND: Although evidence in supporting the associations between childhood maltreatment (CM), parenting style and anxiety in children and adolescents exists, few high-quality analytical epidemiological studies which focusing on clinically diagnosed anxiety disorders (AD) had been published.
OBJECTIVE: The aim of this study was to further corroborate the associations between CM, parenting style, and AD in a large representative sample of Chinese children and adolescents.
METHODS: Study subjects were derived from the Mental Health Survey for Children and Adolescents in Yunnan (MHSCAY), a population-based cross-sectional program.
METHODS: Individually matched case-control study design was adopted. Univariate and multivariate conditional binary logistic regression models were used to estimate the associations between CM, parenting style and AD. Dose-response trends were estimated using the Cochran-Armitage Chi-square test. A series of stratified analyses were conducted to explore effect modification on exposure-outcome association by some important features.
RESULTS: Totally we screened out 202 cases and 404 matched controls, with an age mean of 14.43 years. Conditional logistic regression models revealed that EA and a higher level of parental over-protection were significantly associated with increased risk of AD, with adjusted ORs of 3.39 (95 % CI: 2.07-5.56) and 1.93 (95 % CI: 1.28-2.90). Stratified analysis identified noticeable effect modification by sex, age, and whether the only child in the family.
CONCLUSIONS: Major findings of this study suggested that children and adolescents who had experienced EA or raised up by over-protective parents are at increased risk of AD. Targeted intervention measures should be developed and implemented for these high-risk youths.
OBJECTIVE: The aim of this study was to further corroborate the associations between CM, parenting style, and AD in a large representative sample of Chinese children and adolescents.
METHODS: Study subjects were derived from the Mental Health Survey for Children and Adolescents in Yunnan (MHSCAY), a population-based cross-sectional program.
METHODS: Individually matched case-control study design was adopted. Univariate and multivariate conditional binary logistic regression models were used to estimate the associations between CM, parenting style and AD. Dose-response trends were estimated using the Cochran-Armitage Chi-square test. A series of stratified analyses were conducted to explore effect modification on exposure-outcome association by some important features.
RESULTS: Totally we screened out 202 cases and 404 matched controls, with an age mean of 14.43 years. Conditional logistic regression models revealed that EA and a higher level of parental over-protection were significantly associated with increased risk of AD, with adjusted ORs of 3.39 (95 % CI: 2.07-5.56) and 1.93 (95 % CI: 1.28-2.90). Stratified analysis identified noticeable effect modification by sex, age, and whether the only child in the family.
CONCLUSIONS: Major findings of this study suggested that children and adolescents who had experienced EA or raised up by over-protective parents are at increased risk of AD. Targeted intervention measures should be developed and implemented for these high-risk youths.
摘要：
背景：尽管有证据支持儿童虐待（CM）之间的关联，儿童和青少年中存在父母教养方式和焦虑，针对临床诊断焦虑症(AD)的高质量分析流行病学研究很少发表.
目的：本研究的目的是进一步证实CM，父母教养方式,和AD在中国儿童和青少年的大量代表性样本中。
方法：研究对象来自云南省儿童和青少年心理健康调查（MHSCAY），基于人口的横断面计划。
方法：采用单独匹配的病例对照研究设计。单变量和多变量条件二元逻辑回归模型用于估计CM，父母教养方式和AD。使用Cochran-Armitage卡方检验估计剂量反应趋势。进行了一系列分层分析，以探索一些重要特征对暴露结果关联的影响修改。
结果：共筛选出202例病例和404个匹配对照，平均年龄14.43岁。条件logistic回归模型显示EA和更高水平的父母过度保护与AD风险增加显著相关。调整后的OR为3.39（95%CI：2.07-5.56）和1.93（95%CI：1.28-2.90）。分层分析确定了按性别划分的明显效应修饰，年龄,以及家庭中唯一的孩子。
结论：这项研究的主要发现表明，经历过EA或由过度保护的父母抚养长大的儿童和青少年患AD的风险增加。应针对这些高危青年制定和实施有针对性的干预措施。
目的：本研究的目的是进一步证实CM，父母教养方式,和AD在中国儿童和青少年的大量代表性样本中。
方法：研究对象来自云南省儿童和青少年心理健康调查（MHSCAY），基于人口的横断面计划。
方法：采用单独匹配的病例对照研究设计。单变量和多变量条件二元逻辑回归模型用于估计CM，父母教养方式和AD。使用Cochran-Armitage卡方检验估计剂量反应趋势。进行了一系列分层分析，以探索一些重要特征对暴露结果关联的影响修改。
结果：共筛选出202例病例和404个匹配对照，平均年龄14.43岁。条件logistic回归模型显示EA和更高水平的父母过度保护与AD风险增加显著相关。调整后的OR为3.39（95%CI：2.07-5.56）和1.93（95%CI：1.28-2.90）。分层分析确定了按性别划分的明显效应修饰，年龄,以及家庭中唯一的孩子。
结论：这项研究的主要发现表明，经历过EA或由过度保护的父母抚养长大的儿童和青少年患AD的风险增加。应针对这些高危青年制定和实施有针对性的干预措施。
