合成,抗炎活性,新型吡辛醇衍生物作为 NF - κ B 激活抑制剂的分子对接研究。
关键词: MtROS NF-κB anti-inflammatory activity ginsenosides molecular docking pyxinol derivatives synthesis
Mesh : Molecular Docking Simulation NF-kappa B / metabolism antagonists & inhibitors Mice Animals RAW 264.7 Cells Anti-Inflammatory Agents / pharmacology chemical synthesis chemistry Nitric Oxide / metabolism Reactive Oxygen Species / metabolism Signal Transduction / drug effects Lipopolysaccharides / pharmacology Humans Nitric Oxide Synthase Type II / metabolism antagonists & inhibitors Structure-Activity Relationship
来 源:
DOI:10.3390/molecules29081711
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