PDF(Pubmed)
Abstract：
Acute canine polyradiculoneuritis (ACP) is a common peripheral neuropathy in dogs, and is generally self-limiting and benign. Electrodiagnostic (EDX) tests are typically performed after 7-10 days. Delaying the definitive diagnosis may hamper the treatment of other causes of acute weakness, which may require specific treatments and may carry different prognoses. This retrospective multicenter study aims to assess whether EDX performed within the first 6 days of clinical signs onset can detect alterations indicative of ACP, and aims to characterize the most prevalent alterations. A total of 71 dogs with suspected ACP were retrospectively analyzed and classified into two groups based on EDX timing: early group (EG, 1-6 days after symptom onset) and late group (LG, 7-15 days after symptom onset). In our study, no significant differences were found between the two groups in motor nerve conduction studies (MNCSs) and F-wave analysis, indicating that EDX is able to demonstrate abnormalities even in the first 6 days from onset. Although the LG showed significantly greater degrees of electromyographic (EMG) alterations compared to the EG, frequent muscle alterations were still observed in the EG group. These findings support the use of EDX in patients with suspected ACP within the first 6 days from the clinical onset. Prompt neurophysiological examinations for suspected ACP patients can be performed effectively and can help allow for early diagnosis and facilitate appropriate treatment.
摘要：
急性犬多发性神经根炎（ACP）是犬常见的周围神经病变，通常是自限性和良性的。电诊断(EDX)测试通常在7-10天后进行。延迟明确诊断可能会妨碍其他急性虚弱原因的治疗，这可能需要特定的治疗方法，并且可能具有不同的预后。这项回顾性多中心研究旨在评估在临床体征发作的前6天内进行的EDX是否可以检测到指示ACP的改变。并旨在表征最普遍的改变。对71只疑似ACP的犬进行回顾性分析，并根据EDX时机将其分为两组：早期组（EG，症状发作后1-6天）和晚期组（LG，症状发作后7-15天）。在我们的研究中,在运动神经传导研究（MNCSs）和F波分析中，两组之间没有发现显着差异。表明EDX即使在发病后的前6天也能表现出异常。尽管与EG相比，LG显示出明显更大程度的肌电图（EMG）改变，EG组仍观察到频繁的肌肉改变.这些发现支持在临床发病后的前6天内在疑似ACP患者中使用EDX。可以有效地对可疑ACP患者进行及时的神经生理检查，并有助于早期诊断并促进适当的治疗。
