PDF(Pubmed)
Abstract：
Central nervous system tumors produce adverse outcomes in daily life, although low-grade gliomas are rare in adults. In neurological clinics, the state of impairment of executive functions goes unnoticed in the examinations and interviews carried out. For this reason, the objective of this study was to describe the executive function of a 59-year-old adult neurocancer patient. This study is novel in integrating and demonstrating biological effects and outcomes in performance evaluated by a neuropsychological instrument and psychological interviews. For this purpose, pre- and post-evaluations were carried out of neurological and neuropsychological functioning through neuroimaging techniques (iRM, spectroscopy, electroencephalography), hospital medical history, psychological interviews, and the Wisconsin Card Classification Test (WCST). There was evidence of deterioration in executive performance, as evidenced by the increase in perseverative scores, failure to maintain one\'s attitude, and an inability to learn in relation to clinical samples. This information coincides with the evolution of neuroimaging over time. Our case shows that the presence of the tumor is associated with alterations in executive functions that are not very evident in clinical interviews or are explicit in neuropsychological evaluations. In this study, we quantified the degree of impairment of executive functions in a patient with low-grade glioma in a middle-income country where research is scarce.
摘要：
中枢神经系统肿瘤在日常生活中产生不良结局，尽管低级别胶质瘤在成人中很少见。在神经诊所，在进行的考试和面试中，行政职能受损的状态没有被注意到。出于这个原因,本研究的目的是描述一名59岁的成年神经癌患者的执行功能.这项研究在整合和证明通过神经心理学工具和心理访谈评估的生物学效果和结果方面是新颖的。为此,通过神经影像学技术(iRM，光谱学,脑电图)，医院病史,心理访谈,和威斯康星卡分类测试（WCST）。有证据表明高管绩效恶化，毅力分数的增加证明了这一点，未能保持自己的态度，并且无法学习与临床样本有关的信息。这些信息与神经成像随时间的演变相吻合。我们的病例表明，肿瘤的存在与执行功能的改变有关，这些改变在临床访谈中并不十分明显，或者在神经心理学评估中也很明显。在这项研究中,我们量化了在研究匮乏的中等收入国家的一名低级别胶质瘤患者的执行功能受损程度.
