Abstract：
Although the antagonistic effects of host resistance against biotrophic and necrotrophic pathogens have been documented in various plants, the underlying mechanisms are unknown. Here, we investigated the antagonistic resistance mediated by the transcription factor ETHYLENE-INSENSITIVE3-LIKE 3 (OsEIL3) in rice. The Oseil3 mutant confers enhanced resistance to the necrotroph Rhizoctonia solani but greater susceptibility to the hemibiotroph Magnaporthe oryzae and biotroph Xanthomonas oryzae pv. oryzae. OsEIL3 directly activates OsERF040 transcription while repressing OsWRKY28 transcription. The infection of R. solani and M. oryzae or Xoo influences the extent of binding of OsEIL3 to OsWRKY28 and OsERF040 promoters, resulting in the repression or activation of both salicylic acid (SA)- and jasmonic acid (JA)-dependent pathways and enhanced susceptibility or resistance, respectively. These results demonstrate that the distinct effects of plant immunity to different pathogen types are determined by two transcription factor modules that control transcriptional reprogramming and the SA and JA pathways.
摘要：
尽管已经在各种植物中证明了宿主对生物营养和坏死病原体的抗性的拮抗作用，潜在的机制是未知的。这里,我们研究了水稻中转录因子乙烯-insensitive3-like3（OSEIL3）介导的拮抗抗性。Oseil3突变体赋予对枯萎病菌的抗性增强，但对半生物性稻瘟病菌和生物性稻黄单胞菌pv的敏感性更高。稻米.OsEIL3直接激活OsERF040转录，同时抑制OsWRKY28转录。Solani和米曲霉或Xoo的感染影响OsEIL3与OsWRKY28和OsERF040启动子的结合程度，导致水杨酸（SA）和茉莉酸（JA）依赖性途径的抑制或激活，并增强敏感性或抗性，分别。这些结果表明，植物对不同病原体类型的免疫的不同作用是由控制转录重编程的两个转录因子模块以及SA和JA途径决定的。
