关键词: Alkhumra virus Hemorrhagic fever Meta-analysis Prevalence Tick

Mesh : Animals Humans Africa / epidemiology Asia / epidemiology Camelus / virology Encephalitis Viruses, Tick-Borne Global Health Prevalence Saudi Arabia / epidemiology Ticks / virology

来  源:   DOI:10.1016/j.jiph.2024.04.001

Abstract:
Alkhumra hemorrhagic fever virus (AHFV) has spread beyond the Middle East. However, the actual global prevalence of the virus is yet unknown. This systematic review and meta-analysis, thus, followed the standard reporting guidelines to provide comprehensive details on the prevalence of Alkhumra virus infection globally. The pooled prevalence of AHFV globally was estimated at 1.3% (95% CI: 0.3-6.3), with higher prevalence in humans (3.4%, 95% CI: 0.4-25.0) compared to animals (0.7%, 95% CI: 0.3-1.8). The prevalence in ticks and camels were 0.7% and 0.2%, respectively. Overall, there was a high prevalence rate in Asia (2.6%) compared to Africa (0.5%), and a distinctly higher prevalence in Saudi Arabia (4.6%) compared to other parts of the world (<1%). Lower surveillance rate in humans was observed in recent years. These findings will aid public health preparedness, surveillance, and development of preventive measures due to AHFV\'s potential for outbreaks and severe health consequences.
摘要:
Alkhumra出血热病毒(AHFV)已传播到中东以外。然而,该病毒的实际全球流行程度尚不清楚。本系统综述和荟萃分析,因此,遵循标准报告指南,提供全球Alkhumra病毒感染流行的全面细节.全球AHFV的合并患病率估计为1.3%(95%CI:0.3-6.3),在人类中患病率较高(3.4%,95%CI:0.4-25.0)与动物(0.7%,95%CI:0.3-1.8)。蜱和骆驼的患病率分别为0.7%和0.2%,分别。总的来说,与非洲(0.5%)相比,亚洲(2.6%)的患病率较高,与世界其他地区(<1%)相比,沙特阿拉伯的患病率明显更高(4.6%)。近年来观察到人类的监测率较低。这些发现将有助于公共卫生准备,监视,以及由于AHFV爆发和严重健康后果的可能性而制定的预防措施。
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