Abstract：
Purpose: Oncology clinicians are appropriately positioned to facilitate discussions of assisted reproductive technologies including preimplantation genetic testing for monogenic disease (PGT-M), in the context of cancer treatment or surveillance. Yet, reproductive services, including PGT-M, remain one of the least implemented services in oncology. No studies to date have explored which practice resources the clinicians need to increase knowledge of PGT-M. The objective of this study was to explore the specific needs of oncology clinicians to help maximize the reproductive potential of young adult patients with hereditary cancers. Methods: Participants were recruited through notices circulated on social media platforms and snowball sampling. Participants completed a brief online survey to confirm eligibility. Eligible participants completed a virtual, semi-structured interview. Interviews focused on clinician experiences with PGT-M and initiating referrals to fertility specialists. Thematic analysis was conducted using a constant comparative approach to identify current clinical practices. Results: This study found that PGT-M discussions are not necessarily within the scope of responsibilities for oncology clinicians owing to prioritization of cancer treatment and overall lack of knowledge. Participants need accessible resources and timely support for reproductive planning in the context of cancer treatment. Participants desire a streamlined referral pathway to professionals trained in oncofertility to help address their patient\'s reproductive needs. Conclusion: Our study identified that educational and referral resources to reproductive specialists are needed to maximize reproductive potential across the cancer continuum. These findings provide a foundation for larger studies that can inform standard-of-care recommendations in the emerging field of oncofertility.
摘要：
目的：肿瘤学临床医生处于适当的位置，以促进辅助生殖技术的讨论，包括单基因疾病的植入前遗传检测（PGT-M），在癌症治疗或监测的背景下。然而，生殖服务,包括PGT-M,仍然是肿瘤学中实施最少的服务之一。迄今为止，尚无研究探索临床医生需要哪些实践资源来增加PGT-M的知识。这项研究的目的是探讨肿瘤临床医生的具体需求，以帮助最大限度地提高年轻成年遗传性癌症患者的生殖潜力。方法：通过在社交媒体平台上发布的通知和滚雪球抽样招募参与者。参与者完成了简短的在线调查以确认资格。符合条件的参与者完成了虚拟，半结构化面试。访谈的重点是PGT-M的临床医生经验，并开始转介给生育专家。使用持续的比较方法进行主题分析，以确定当前的临床实践。结果：这项研究发现，由于癌症治疗的优先次序和总体知识的缺乏，PGT-M讨论不一定在肿瘤临床医生的职责范围内。在癌症治疗的背景下，参与者需要可获得的资源和对生殖规划的及时支持。参与者希望有一个简化的转诊途径，以帮助他们的患者的生殖需求满足受训的专业人员。结论：我们的研究发现，需要向生殖专家提供教育和转诊资源，以最大程度地提高整个癌症连续体的生殖潜力。这些发现为更大的研究提供了基础，这些研究可以为新兴的生育领域提供标准的护理建议。
