PDF(Pubmed)
Abstract：
BACKGROUND: Psammomatoid ossifying fibroma (POF) is a rare craniofacial neoplasm, primarily affecting the maxillofacial region, and typically observed in adolescents and young adults. This case report presents a unique occurrence of POF in a 50-year-old male, defying the conventional age range and exhibiting an unusual anatomical location within the frontal sinus.
METHODS: A 50-year-old male with a prior history of cecal adenocarcinoma and colectomy presented with left eye proptosis and new-onset headaches. Imaging revealed a well-defined calcified mass in the left frontal sinus, leading to a diagnosis of POF. Open surgical resection was performed to remove the tumor, and histopathological evaluation confirmed its diagnosis as psammomatoid ossifying fibroma. The patient exhibited no postoperative complications or signs of recurrence.
CONCLUSIONS: This case underscores the diverse clinical presentations and diagnostic challenges associated with POF, emphasizing the importance of accurate diagnosis and multidisciplinary collaboration. Further research is needed to explore the genetic underpinnings and optimal management strategies for this intriguing condition.
METHODS: A 50-year-old male with a prior history of cecal adenocarcinoma and colectomy presented with left eye proptosis and new-onset headaches. Imaging revealed a well-defined calcified mass in the left frontal sinus, leading to a diagnosis of POF. Open surgical resection was performed to remove the tumor, and histopathological evaluation confirmed its diagnosis as psammomatoid ossifying fibroma. The patient exhibited no postoperative complications or signs of recurrence.
CONCLUSIONS: This case underscores the diverse clinical presentations and diagnostic challenges associated with POF, emphasizing the importance of accurate diagnosis and multidisciplinary collaboration. Further research is needed to explore the genetic underpinnings and optimal management strategies for this intriguing condition.
摘要：
背景：沙瘤样骨化性纤维瘤（POF）是一种罕见的颅面肿瘤，主要影响颌面部区域，通常在青少年和年轻人中观察到。此病例报告显示了一名50岁男性的POF独特发生，无视传统的年龄范围，并在额窦内表现出不寻常的解剖位置。
方法：一名50岁男性，既往有盲肠腺癌和结肠切除术史，表现为左眼眼球突出和新发头痛。影像学显示左额窦有明确的钙化肿块，导致POF的诊断。进行了开放性手术切除肿瘤，组织病理学评估证实其诊断为沙瘤样骨化性纤维瘤。患者未出现术后并发症或复发迹象。
结论：该病例强调了与POF相关的各种临床表现和诊断挑战，强调准确诊断和多学科协作的重要性。需要进一步的研究来探索这种有趣的条件的遗传基础和最佳管理策略。
方法：一名50岁男性，既往有盲肠腺癌和结肠切除术史，表现为左眼眼球突出和新发头痛。影像学显示左额窦有明确的钙化肿块，导致POF的诊断。进行了开放性手术切除肿瘤，组织病理学评估证实其诊断为沙瘤样骨化性纤维瘤。患者未出现术后并发症或复发迹象。
结论：该病例强调了与POF相关的各种临床表现和诊断挑战，强调准确诊断和多学科协作的重要性。需要进一步的研究来探索这种有趣的条件的遗传基础和最佳管理策略。
