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Abstract：
Autophagy is a cellular catabolic process characterized by the formation of double-membrane autophagosomes. Transmission electron microscopy is the most rigorous method to clearly visualize autophagic engulfment and degradation. A large number of studies have shown that autophagy is closely related to the digestion, secretion, and regeneration of gastrointestinal (GI) cells. However, the role of autophagy in GI diseases remains controversial. This article focuses on the morphological and biochemical characteristics of autophagy in GI diseases, in order to provide new ideas for their diagnosis and treatment.
摘要：
自噬是一种以双膜自噬体形成为特征的细胞分解代谢过程。透射电子显微镜是最严格的方法，可以清楚地看到自噬吞噬和降解。大量研究表明自噬与消化密切相关,分泌，和胃肠(GI)细胞的再生。然而,自噬在胃肠道疾病中的作用仍存在争议。本文重点介绍自噬在胃肠道疾病中的形态学和生化特征,为其诊断和治疗提供新的思路。
