关键词: Clinical management Diagnostic criteria Left Ventricular Noncompaction Pathophysiology Prognostic assessments

Mesh : Humans Isolated Noncompaction of the Ventricular Myocardium / diagnosis therapy physiopathology Adult Disease Management

来  源:   DOI:10.1016/j.cpcardiol.2024.102571

Abstract:
In the realm of cardiovascular health, isolated left ventricular noncompaction (LVNC) stands out for its distinct morphological features and the clinical challenges it presents, particularly in adults. This literature review explores the intricacies of LVNC, aiming to unravel its epidemiological spread, diagnostic hurdles, and therapeutic strategies. Despite technological advancements in cardiac imaging that have improved the recognition of LVNC, a significant gap persists alongside a fragmented understanding of its pathogenesis. The studies scrutinized reveal a broad spectrum of prevalence rates influenced by diverse diagnostic tools and demographic variables. This variation underscores the complexity of accurately identifying LVNC and the resultant implications for clinical management. The review succinctly addresses the need for precise guidelines to navigate the diagnosis of LVNC and outlines the imperative for tailored clinical management approaches that cater to the wide array of patient presentations, from asymptomatic cases to those with severe cardiac dysfunction. By highlighting the critical gaps in current literature-namely the absence of standardized diagnostic criteria and a comprehensive pathogenic model-the review sets the stage for future research directions. These endeavors are essential for enhancing diagnostic accuracy, refining management protocols, and ultimately improving patient outcomes in this complex subset of cardiomyopathy, thus contributing significantly to the advancement of cardiovascular medicine.
摘要:
在心血管健康领域,孤立的左心室致密化不全(LVNC)因其独特的形态学特征和临床挑战而脱颖而出,尤其是成年人。这篇文献综述探讨了LVNC的复杂性,旨在解开其流行病学传播,诊断障碍,和治疗策略。尽管心脏成像的技术进步提高了对LVNC的认识,除了对其发病机制的零散理解之外,仍然存在明显的差距。仔细检查的研究揭示了受多种诊断工具和人口统计学变量影响的广泛患病率。这种变化强调了准确识别LVNC的复杂性以及对临床管理的影响。该评论简洁地解决了对LVNC诊断的精确指南的需求,并概述了满足广泛患者表现的量身定制的临床管理方法的必要性。从无症状病例到严重心功能不全的患者。通过强调当前文献中的关键差距-即缺乏标准化的诊断标准和全面的致病模型-该综述为未来的研究方向奠定了基础。这些努力对于提高诊断准确性至关重要,炼油管理协议,最终改善了这种复杂的心肌病的患者预后,从而大大促进了心血管医学的发展。
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