Abstract：
Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is a rare but highly aggressive ovarian malignant neoplasm lacking a unified clinical management process. Most patients are diagnosed at an advanced stage and have an extremely poor prognosis with an overall probability of survival less than 10 %. Here, we describe the case of a patient with advanced SCCOHT achieved a survival of over 5 years after receiving multiple cycles of immunotherapy combined with anti-angiogenic therapy or CDK4/6 inhibitors. At the same time, we also summarized the case reports and clinical trials of immunotherapy in SCCOHT.
摘要：
卵巢小细胞癌,高血钙型（SCCOHT）是一种罕见但高度侵袭性的卵巢恶性肿瘤，缺乏统一的临床治疗流程。大多数患者被诊断为晚期，预后极差，总生存率低于10％。这里,我们描述了1例晚期SCCOHT患者在接受多周期免疫治疗联合抗血管生成治疗或CDK4/6抑制剂治疗后生存超过5年.同时,我们还总结了SCCOHT免疫治疗的病例报告和临床试验.
